[Dihydroergotamine as a nasal spray in the therapy of migraine attacks. Efficacy and tolerance].

Author: BremgartnerM F, JenzerG

Paper Details 
Original Abstract of the Article :
In an open multicentre study in Switzerland, the dihydroergotamine nasal spray was studied for its efficacy and tolerability in the treatment of acute migraine attacks (common and classical migraine--one attack each patient) in a total of 904 patients. In the global assessment, 76.8% of all the pati...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/2203127

データ提供:米国国立医学図書館(NLM)

Dihydroergotamine Nasal Spray: A Potential Solution for Migraines

This study investigates the efficacy and tolerability of dihydroergotamine nasal spray in treating acute migraine attacks. The research employed a multicenter study design, involving a significant number of participants (904 patients). The study aimed to evaluate the effectiveness of this treatment option, particularly when administered during the prodromal phase of migraine attacks.

Promising Results and Side-Effect Considerations

The findings suggest that dihydroergotamine nasal spray demonstrated good efficacy in a majority of patients (76.8%). Furthermore, the study found that when used during the prodromal phase, the spray was effective in a considerable proportion of patients (63%). While the nasal spray showed positive results, the study also noted the occurrence of minor side effects, such as nasal irritation, nausea, and dizziness. However, the frequency of these side effects was relatively low, and the majority of patients did not experience significant discomfort.

A Potential Tool for Migraine Management

This study provides evidence that dihydroergotamine nasal spray can be an effective option for managing acute migraine attacks. It suggests that the spray may be particularly beneficial when used during the prodromal phase, potentially preventing the migraine from fully developing. However, it's important to be mindful of potential side effects, especially those related to nasal irritation and dizziness, as they may vary from person to person. It's always essential to consult with your physician to assess whether this treatment option is suitable for you.

Dr.Camel's Conclusion

This research offers a promising avenue for migraine management. Like a camel navigating a desert storm, the nasal spray could provide relief during the turbulent period of a migraine attack. While it's important to acknowledge the potential side effects, the study suggests that dihydroergotamine nasal spray could be a valuable tool for individuals seeking effective migraine relief. Always remember to consult with your healthcare provider to determine the best course of action for your specific needs.

Date :
  1. Date Completed 1990-10-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2203127

DOI: Digital Object Identifier

2203127

Related Literature

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.