[Mood disorder after malaria prophylaxis with mefloquine (two case reports)].

Author: AbilkacemL, LaffintiA, Oueriagli NabihF, TouhamiM

Paper Details 
Original Abstract of the Article :
Mefloquine (Lariam) is the drug of choice as malaria prophylaxis for travel to chloroquine-resistant areas. Severe neuropsychiatric side effects are rare. We report two clinical cases of mood disorders: mania and a major depressive episode with psychotic characteristics in two patients with mefloqui...See full text at original site
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引用元:
https://doi.org/10.1016/j.encep.2011.01.013

データ提供:米国国立医学図書館(NLM)

Mefloquine: A Double-Edged Sword in the Desert of Malaria Prevention

Mefloquine is a powerful weapon in the fight against malaria, a disease that has plagued humanity for centuries, much like a persistent sandstorm in the desert. While it is often used as a preventative measure, this study presents two cases where mefloquine had unexpected and serious side effects, resulting in mood disorders.

The authors describe two cases involving individuals who developed mood disorders after taking mefloquine as malaria prophylaxis. One patient experienced mania with psychotic symptoms, while the other developed a major depressive episode with psychotic characteristics. These cases highlight the potential for mefloquine to have severe neuropsychiatric side effects, even though such reactions are relatively rare.

A Cautionary Tale in the Desert

This study serves as a cautionary tale, reminding us that even seemingly safe medications can have unexpected side effects. It emphasizes the importance of carefully monitoring patients who are taking mefloquine, especially those who experience any changes in mood or behavior.

Navigating the Desert of Medications

This research underscores the importance of being vigilant about potential side effects of medications, even those used for preventative purposes. It's like navigating a desert of medications, where every step requires caution and awareness of potential risks.

Dr.Camel's Conclusion

This study reminds us that even the most effective medications can have unexpected consequences, and the desert of medicine is full of hidden dangers. It underscores the importance of careful monitoring, open communication between patients and healthcare providers, and continued research to better understand the potential risks and benefits of medications.

Date :
  1. Date Completed 2012-05-23
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

22032283

DOI: Digital Object Identifier

10.1016/j.encep.2011.01.013

SNS
PICO Info
in preparation
Languages

French

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