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Selenium and lung cancer: a systematic review and meta analysis.

Author: CooleyKieran, FergussonDean, FernandesRochelle, FritzHeidi, KennedyDeborah, SagarStephen, SeelyAndrew, SeelyDugald, WongRaimond

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Selenium may be effective for lung cancer prevention among individuals with lower selenium status, but at present should not be used as a general strategy for lung cancer prevention. More evidence on the ability of selenium to reduce cisplatin and radiation therapy toxicity is required to ensure that therapeutic efficacy is maintained before any broad clinical recommendations can be made in this context.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Selenium is a natural health product widely used in the treatment and prevention of lung cancers, but large chemoprevention trials have yielded conflicting results. We conducted a systematic review of selenium for lung cancers, and assessed potential interactions with conventional therap...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208545/

データ提供：米国国立医学図書館（NLM）

Selenium and Lung Cancer: A Complex Relationship

This systematic review and meta-analysis delves into the complex relationship between selenium and lung cancer. It's like exploring a desert landscape where the presence of water (selenium) can be both beneficial and detrimental depending on the specific conditions. The research analyzed a vast array of studies to investigate the potential role of selenium in lung cancer prevention and treatment.

Selenium: A Double-Edged Sword in Lung Cancer

The study found that selenium supplementation may reduce the risk of lung cancer in individuals with lower baseline selenium levels, but increase risk in those with higher levels. This is like finding a desert oasis that can provide life-giving water to those in need, but can also become a breeding ground for harmful organisms if overused. This complex relationship underscores the importance of personalized approaches to health interventions.

Understanding Selenium's Role in Lung Health

This research highlights the importance of understanding individual selenium status when considering supplementation. It suggests that selenium may be beneficial for some individuals but potentially harmful to others. This research encourages us to consult with healthcare providers to determine the appropriate approach for managing selenium levels and supporting lung health.

Dr. Camel's Conclusion

The research on selenium and lung cancer reveals the intricate nature of health interventions. It reminds us that what is beneficial for one individual may not be for another. This research underscores the importance of personalized approaches to health care and the need for further research to fully understand the complex interplay between nutrients and disease.

Date :
  1. Date Completed 2012-03-26
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22073154

DOI: Digital Object Identifier

PMC3208545

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PICO Info
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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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