Paper Details

  1. Home
  2. Paper Details

Retrospective review of male breast cancer patients: analysis of tamoxifen-related side-effects.

Author: GiordanoS H, HortobagyiG N, MunsellM F, PemmarajuN

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Tamoxifen, a common antihormonal treatment for male breast cancer, was associated with a high rate of discontinuation due to toxicity. The most frequent toxicities reported were weight gain and sexual dysfunction. Prospective studies are needed to evaluate the safety and efficacy of antihormonal agents specifically for male breast cancer.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Approximately 2000 American men are diagnosed with breast cancer every year. Limited data are available evaluating toxicity of antihormonal treatments in male breast cancer patients. PATIENTS AND METHODS: We reviewed male breast cancer patients evaluated at our institution (1999-2009). ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493137/

データ提供：米国国立医学図書館（NLM）

Tamoxifen-Related Side Effects in Male Breast Cancer Patients

This study delves into the world of male breast cancer, a condition often overlooked in the realm of cancer research. Imagine a camel caravan traversing a vast desert, and one of the camels falls ill. This is akin to male breast cancer, a relatively rare but serious disease. The researchers focused on the side effects of tamoxifen, a common treatment for breast cancer, in men. They were particularly interested in understanding the toxicity profile of this drug, as the available data was limited.

Navigating the Side Effects of Tamoxifen

The research revealed that a significant number of male patients experienced side effects from tamoxifen, with the most common being weight gain and sexual dysfunction. This is like having a camel in the caravan experience a sudden change in its ability to navigate the desert, requiring additional resources and adjustments to the journey. The study also found that a considerable number of patients discontinued tamoxifen due to these side effects.

The Importance of Tailored Treatment Approaches

This research highlights the need for further investigation into the optimal treatment strategies for male breast cancer patients. It is crucial to understand the unique toxicity profiles of medications and to develop tailored treatment approaches that minimize side effects. This is like having a knowledgeable guide who understands the needs of each camel in the caravan, allowing them to navigate the desert with minimal challenges.

Dr.Camel's Conclusion

This study sheds light on the importance of considering the unique needs of male breast cancer patients. It emphasizes the need for further research and development of personalized treatment approaches that minimize side effects and improve the quality of life for those affected by this disease. As we continue to explore the vast landscapes of cancer research, we must remember to treat each patient, each camel in the caravan, with the utmost care and attention.

Date :
  1. Date Completed 2012-09-20
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

22085764

DOI: Digital Object Identifier

PMC3493137

Related Literature

Article Analysis
・Side Effects of tamoxifen
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.