"7, 10 and 14-days rabeprazole-based standard triple therapies for H. pylori eradication: are they still effective? A randomized trial".

Author: FragkouP, GeorgopoulosS D, KaratapanisS, KouvidouC, LisgosPh, MentisA, PapantoniouN, PapastergiouV, SkordaL

Paper Details 
Original Abstract of the Article :
Increasing data suggests that the efficiency of standard triple therapies of 7-10-14 days duration has fallen below the threshold for acceptability (80% cure rates in intention to treat analysis). Use of rabeprazole, a PPI less influenced by CYP2C19 gene polymorphisms is reported to lead to improved...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/22103045

データ提供:米国国立医学図書館(NLM)

Eradicating H. pylori: A New Desert Oasis?

This study embarks on a journey through the world of H. pylori eradication, exploring the effectiveness of different treatment regimens for this common bacterial infection. The researchers investigated the efficacy of rabeprazole-based triple therapies of varying durations (7, 10, and 14 days) in a randomized trial, a scientific approach as precise as a camel's keen sense of direction.

A promising path: Rabeprazole-based triple therapy

The study found that rabeprazole-based triple therapies, despite concerns about declining eradication rates, remained effective for eradicating H. pylori. This finding, like a well-charted route across the desert, provides clinicians with a valuable tool for combating this persistent infection. The researchers also emphasized the importance of optimizing treatment regimens to ensure high eradication rates and prevent the development of resistance.

Optimizing treatment: A balanced approach

This research underscores the importance of ongoing research and evaluation of treatment regimens for H. pylori infection. It provides valuable insights into the effectiveness of rabeprazole-based triple therapies and highlights the need for a balanced approach that considers the individual needs of each patient and the evolving landscape of antimicrobial resistance.

Dr.Camel's Conclusion

This study sheds light on the ongoing battle against H. pylori infection, a tenacious foe in the desert of human health. The research highlights the importance of continually refining treatment strategies to ensure optimal outcomes and prevent the emergence of resistance. It underscores the importance of a collaborative approach involving healthcare professionals and researchers to combat this persistent challenge.

Date :
  1. Date Completed 2011-12-20
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

22103045

DOI: Digital Object Identifier

22103045

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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