Paper Details

  1. Home
  2. Paper Details

A double-masked study to compare the efficacy and safety of topical cromolyn for the treatment of allergic conjunctivitis.

Author: ChenWei-Li, HouYu-Chih, HuFung-Rong, LiuYao-lin, WangI-Jong

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cromolyn ophthalmic solution, both with and without preservative, was effective and safe for treating allergic conjunctivitis. While both formulations were equally effective, preservative-free cromolyn may be beneficial for patients with compromised eyes or those requiring long-term treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND/PURPOSE: To compare the efficacy and safety of topical cromolyn between with and without preservative for the treatment of allergic conjunctivitis. METHODS: A double-masked study was performed in patients with allergic conjunctivitis. Each cromolyn sodium 2% ophthalmic solution with or w...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.jfma.2011.09.004

データ提供：米国国立医学図書館（NLM）

Topical Cromolyn for Allergic Conjunctivitis: A Desert Oasis for Itchy Eyes

Allergic conjunctivitis, a common eye condition, can be as irritating as a sandstorm in the desert. This research compares the efficacy and safety of topical cromolyn ophthalmic solutions, both with and without preservatives, in treating allergic conjunctivitis. The researchers used a double-blind, crossover design, like a camel race where neither the camels nor the judges know who is who. They aimed to see if the preservatives affected the effectiveness of the treatment.

Cromolyn: An Oasis of Relief for Itchy Eyes

The results demonstrated that both cromolyn solutions with and without preservatives were effective in treating allergic conjunctivitis, reducing symptoms like itching, redness, and foreign body sensation. This is like having two camels, each finding a way to navigate the desert and reach the oasis of relief. However, the researchers found that the preservative-free cromolyn solution was better at reducing corneal erosion, potentially making it a better option for individuals with compromised eyes.

Protecting Your Eyes: A Desert Oasis of Care

This research highlights the importance of considering both efficacy and safety when choosing treatments for allergic conjunctivitis. While both cromolyn solutions were effective, the preservative-free version might be a better option for certain individuals, especially those with compromised eyes. Consult with your doctor to determine the best treatment for your specific needs.

Dr.Camel's Conclusion

This research offers a valuable guide for treating allergic conjunctivitis, a condition as common as sand dunes in the desert. Both cromolyn solutions with and without preservatives were effective, but the preservative-free version may offer additional benefits for certain individuals. Choosing the right treatment for your specific needs is crucial for finding relief and protecting your precious eyes.

Date :
  1. Date Completed 2012-03-20
  2. Date Revised 2016-10-13
Further Info :

Pubmed ID

22118312

DOI: Digital Object Identifier

10.1016/j.jfma.2011.09.004

Related Literature

Article Analysis
・Effects of cromolyn ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.