Treatment of postmenopausal osteoporosis with high doses of synthetic calcitriol. A randomized controlled study.

Author: GallagherJ C, GoldgarD

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To study the efficacy of synthetic 1,25 dihydroxyvitamin D3 (calcitriol) in the treatment of osteoporosis. DESIGN: Two-year, double-blind, randomized clinical trial. SETTING: University medical center. PATIENTS: Fifty postmenopausal women with vertebral fractures recruited by referral....See full text at original site
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引用元:
https://doi.org/10.7326/0003-4819-113-9-649

データ提供:米国国立医学図書館(NLM)

Calcitriol Treatment for Postmenopausal Osteoporosis: A Promising Approach

Osteoporosis, characterized by weakened bones, affects millions of people worldwide. This randomized controlled study investigates the efficacy of calcitriol, a synthetic form of vitamin D3, in treating postmenopausal osteoporosis. The study followed 50 women with vertebral fractures for two years, comparing the effects of calcitriol with placebo.

Calcitriol Improves Bone Mineral Density

The study found that calcitriol therapy significantly increased bone mineral density of the spine, while placebo led to a decrease in bone density. This suggests that calcitriol can effectively combat bone loss associated with osteoporosis. The study also observed no adverse effects on renal function after long-term calcitriol therapy.

Maintaining Bone Health: The Importance of Vitamin D

This study emphasizes the importance of adequate vitamin D levels in maintaining bone health. It suggests that calcitriol could be a valuable tool for preventing and managing osteoporosis, particularly in postmenopausal women. However, like a camel carefully navigating the desert, individuals should consult with their healthcare providers to determine the appropriate dose and duration of calcitriol therapy.

Dr.Camel's Conclusion

The desert of osteoporosis can be a challenging one to navigate, but this research suggests that calcitriol might be a valuable resource in combating this condition. It's a reminder that even in the driest of environments, there are ways to build strength and resilience.

Date :
  1. Date Completed 1990-11-15
  2. Date Revised 2019-06-19
Further Info :

Pubmed ID

2221645

DOI: Digital Object Identifier

10.7326/0003-4819-113-9-649

SNS
PICO Info
in preparation
Languages

English

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