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High-dose therapy with autologous stem cell transplantation versus chemotherapy or immuno-chemotherapy for follicular lymphoma in adults.

Author: BorchmannPeter, EngertAndreas, ReiserMarcel, SchaafMarkus, SkoetzNicole

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

High-dose therapy (HDT) followed by autologous stem cell transplantation (ASCT) is an option for patients with follicular lymphoma (FL) in advanced stages or for second-line therapy. While it improves progression-free survival (PFS), there is a potential for increased risk of second cancers.
Paper Details　
Original Abstract of the Article :
Follicular lymphoma (FL) is the most common indolent and second most common Non-Hodgkin`s lymphoma (NHL) in the Western world. Standard treatment usually includes rituximab and chemotherapy. High-dose therapy (HDT) followed by autologous stem cell transplantation (ASCT) is an option for patients in ...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD007678.pub2

データ提供：米国国立医学図書館（NLM）

High-Dose Therapy and Autologous Stem Cell Transplantation: A New Path in the Desert of Follicular Lymphoma

Follicular lymphoma (FL), a type of non-Hodgkin's lymphoma, can be a challenging condition to manage. This study investigates the role of high-dose therapy (HDT) followed by autologous stem cell transplantation (ASCT) as a treatment option for FL. The authors reviewed the existing literature to assess the efficacy and potential risks of this approach, offering valuable insights for clinicians and patients facing this complex diagnosis.

HDT and ASCT: A Potential Weapon Against Follicular Lymphoma

The study suggests that HDT and ASCT can improve progression-free survival rates in patients with FL. While this approach has shown promise in treating advanced FL and as a second-line therapy, further research is needed to fully understand its long-term impact, particularly regarding the potential risk of secondary cancers. Careful consideration of individual factors, such as age, disease stage, and overall health, is crucial when evaluating the potential benefits and risks of this approach.

Finding the Right Path in Follicular Lymphoma Treatment

The study highlights the ongoing need for research and personalized treatment approaches for FL. While HDT and ASCT offer a potential weapon in the fight against this complex disease, careful evaluation of individual factors and ongoing research are essential to ensure optimal patient outcomes. For those navigating the desert of FL treatment, collaboration with healthcare professionals and access to the latest research are crucial for making informed decisions about treatment options.

Dr. Camel's Conclusion

Follicular lymphoma can be a challenging journey, but research continues to uncover new paths toward effective treatment. HDT and ASCT offer a potential oasis in the desert of FL treatment, but careful consideration and ongoing research are essential to ensure the best possible outcomes for patients.

Date :
  1. Date Completed 2012-06-26
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

22258971

DOI: Digital Object Identifier

10.1002/14651858.CD007678.pub2

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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