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Failure of pre-emptive treatment of cytomegalovirus infections and antiviral resistance in stem cell transplant recipients.

Author: ClaasEric C J, HalkesConstantijn J M, KroesAloys C M, MarijtErik W A F, VossenAnn C T M, WolterbeekRon, van der BeekMartha T, van der Blij-de BrouwerCaroline S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Pre-emptive treatment for CMV infections after stem cell transplantation is often ineffective due to viral resistance or immune failure. This study investigated risk factors for treatment failure and the role of antiviral resistance.
Paper Details　
Original Abstract of the Article :
Treatment of cytomegalovirus (CMV) infections after stem cell transplantation (SCT) does not always lead to a rapid viral response. The causes of treatment failure may be either viral resistance or immunological failure to control viral replication. This study investigated the response to pre-emptiv...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.3851/IMP1899

データ提供：米国国立医学図書館（NLM）

Challenges in Pre-emptive Treatment of Cytomegalovirus Infections

As researchers, we strive to understand and combat the ever-evolving landscape of infectious diseases. This study delves into the complex world of cytomegalovirus (CMV) infections in stem cell transplant recipients. The researchers investigated the effectiveness of pre-emptive treatment for CMV infections in this vulnerable population, exploring the factors that may contribute to treatment failure.

The Complexities of Cytomegalovirus Infections in Transplant Recipients

The study found that pre-emptive treatment for CMV infections in stem cell transplant recipients did not always lead to a rapid viral response. Treatment failure was attributed to both viral resistance and immunological deficiencies. It's like navigating a desert where the terrain is constantly shifting, making it difficult to predict the path ahead.

The Importance of Monitoring and Adapting Treatment Strategies

This study underscores the importance of monitoring for viral resistance and adapting treatment strategies accordingly. It highlights the need for a multi-faceted approach to managing CMV infections in stem cell transplant recipients.

Dr. Camel's Conclusion

This research sheds light on the complexities of managing CMV infections in stem cell transplant recipients. It underscores the need for vigilance in monitoring for viral resistance and for adapting treatment strategies to address the unique challenges of this patient population.

Date :
  1. Date Completed 2013-02-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22267468

DOI: Digital Object Identifier

10.3851/IMP1899

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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