A randomized clinical trial comparing meglumine antimoniate, pentamidine and amphotericin B for the treatment of cutaneous leishmaniasis by Leishmania guyanensis.

Author: FerreiraLuiz Carlos de Lima, GadelhaEllen Priscilla Nunes, GuerraJorge Augusto de Oliveira, NevesLeandro Ourives, Silva JúniorRoberto Moreira da, TalhariAnette Chrusciak, TalhariSinésio

Paper Details 
Original Abstract of the Article :
American tegumentary leishmaniasis (ATL) treatment remains a challenge, since most available drugs are injectable and only a small number of comparative, randomized clinical trials have been performed to support their use. Moreover, treatment outcome may depend on the causative species of Leishmania...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1590/s0365-05962011000600005

データ提供:米国国立医学図書館(NLM)

Treating Leishmaniasis: A Comparison of Antimonial Drugs

This study investigates the effectiveness of three different drugs in treating cutaneous leishmaniasis, a parasitic infection that affects the skin. Imagine it as a race against time in a scorching desert – we need the right tools to combat this persistent infection. The researchers compared the efficacy of meglumine antimoniate, pentamidine, and amphotericin B in patients infected with *Leishmania guyanensis*, a common cause of leishmaniasis.

A Search for the Optimal Weapon

The researchers sought to determine which of these three medications is the most effective treatment for cutaneous leishmaniasis. It's like choosing the right weapon for a sandstorm – each medication offers a different approach to combating the infection. This research aims to identify the most effective strategy for treating this challenging disease.

Finding the Best Solution for Leishmaniasis

This research highlights the importance of clinical trials in evaluating and comparing different treatment options for infectious diseases. It's like conducting a thorough search for the best way to navigate a challenging desert landscape. The researchers' findings provide valuable insights for physicians treating patients with leishmaniasis, ultimately leading to better patient care.

Dr. Camel's Conclusion

This research underscores the importance of conducting clinical trials to compare different treatment options for infectious diseases. It's a reminder that the quest for effective treatments is an ongoing journey, and that by comparing and evaluating different approaches, we can find the most effective solutions for our patients.

Date :
  1. Date Completed 2012-09-28
  2. Date Revised 2021-03-31
Further Info :

Pubmed ID

22281895

DOI: Digital Object Identifier

10.1590/s0365-05962011000600005

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.