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Clinical observations on safety and efficacy of OxyContin® administered by rectal route in treating cancer related pain.

Author: HuangXin-En, LiCheng-Guang, LiYing, LuYan-Yan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

OxyContin administered by the rectal route was found to be safe and effective in controlling pain in patients with advanced cancer. The main side effects were constipation, flatulence, and fatigue.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To determine the efficacy and adverse reactions of OxyContin® administered by rectal route in advanced cancer patients. METHODS: Patients were enrolled into this study in which OxyContin was administered by the rectal route. The visual analogue scale (VAS) was applied to score pain inten...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/22320941

データ提供：米国国立医学図書館（NLM）

OxyContin® for Cancer-Related Pain: A Rectal Route Investigation

This study explores the efficacy and safety of OxyContin®, a potent opioid analgesic, administered rectally for the management of cancer-related pain. The researchers enrolled patients with advanced cancer and evaluated the effectiveness of rectal OxyContin in reducing pain intensity as measured by the visual analog scale (VAS). They also monitored for adverse events using the National Cancer Institute-Common Toxicity Criteria (NCI-CTC). The results showed that rectal OxyContin significantly reduced pain intensity, with a notable decrease in VAS scores. The most common side effects were constipation, flatulence, and fatigue, with no significant elevation in liver or kidney function markers.

Easing the Burden of Cancer Pain: A Gentle Approach

This study offers a promising alternative for managing cancer-related pain, utilizing rectal administration of OxyContin®. The rectal route provides a convenient and effective way to deliver pain medication, potentially reducing the need for more invasive approaches. It's like finding a hidden oasis in a vast and arid landscape, providing a source of relief for those suffering from the debilitating effects of cancer pain.

Navigating the Sands of Pain Management

This research emphasizes the importance of finding innovative and safe solutions for managing pain, particularly for patients with advanced cancer. The use of rectal OxyContin® presents a potential avenue for improving pain control while minimizing some of the potential risks associated with other routes of administration. It's like a camel navigating a complex maze of sand dunes, searching for the most effective path to reach its destination.

Dr.Camel's Conclusion

This study demonstrates the potential of rectal OxyContin® as a safe and effective option for managing cancer-related pain. It offers hope for patients seeking relief from this debilitating symptom, reminding us that innovation and compassion are crucial elements in providing quality care.

Date :
  1. Date Completed 2012-06-28
  2. Date Revised 2017-03-08
Further Info :

Pubmed ID

22320941

DOI: Digital Object Identifier

22320941

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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