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Discontinuation of antidepressants in people with dementia and neuropsychiatric symptoms (DESEP study): double blind, randomised, parallel group, placebo controlled trial.
Author: BerghSverre, EngedalKnut, SelbækGeir
Original Abstract of the Article :
OBJECTIVE: To determine the effect of discontinuing antidepressant treatment in people with dementia and neuropsychiatric symptoms. DESIGN: Double blind, randomised, parallel group, placebo controlled trial. SETTING: Norwegian nursing homes; residents recruited by 16 study centres in Norway from A...See full text at original site
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引用元:
https://doi.org/10.1136/bmj.e1566
データ提供:米国国立医学図書館(NLM)
Antidepressants and Dementia: A Balancing Act
The world of dementia, a progressive decline in cognitive function, often comes with a myriad of challenges, including neuropsychiatric symptoms. This research investigates the impact of discontinuing antidepressant treatment in individuals with dementia and neuropsychiatric symptoms, exploring the potential benefits and risks associated with this decision. This is like navigating a delicate balance in the desert, where the absence of one element can have significant consequences on the ecosystem.
Discontinuation of Antidepressants: A Potential Increase in Depressive Symptoms
The study reveals that discontinuing antidepressant treatment in individuals with dementia and neuropsychiatric symptoms leads to an increase in depressive symptoms, compared to those who continue treatment. This is like disrupting a delicate ecosystem in the desert, where the removal of a key element can lead to an imbalance and a decline in overall health. The study highlights the importance of carefully considering the potential risks and benefits of discontinuing antidepressant treatment in this population, weighing the possibility of increased depressive symptoms against the potential for adverse effects associated with continued treatment.
Navigating the Challenges of Dementia: A Multifaceted Approach
This research emphasizes the importance of a multifaceted approach to managing dementia and its associated neuropsychiatric symptoms. The study underscores the need for careful consideration of the benefits and risks associated with antidepressant treatment in this population, as well as the importance of individualized care plans tailored to each patient's unique needs. This is like navigating a complex desert landscape, where each path requires a different strategy and careful planning to reach the desired destination.
Dr.Camel's Conclusion
This research provides valuable insights into the challenges of managing dementia and its associated neuropsychiatric symptoms. Discontinuing antidepressant treatment in this population can lead to an increase in depressive symptoms, highlighting the importance of carefully considering the potential risks and benefits of this decision. The study emphasizes the need for a multifaceted approach to dementia care, including individualized care plans that address the unique needs of each patient.
Date :
- Date Completed 2012-05-01
- Date Revised 2022-04-08
Further Info :
Related Literature
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