Effect of oral cholecalciferol 2,000 versus 5,000 IU on serum vitamin D, PTH, bone and muscle strength in patients with vitamin D deficiency.

Author: DiamondT, GolombickT, WongY K

Paper Details 
Original Abstract of the Article :
Treatment of vitamin D deficiency for 3 months with oral cholecalciferol 5,000 IU daily was more effective than 2,000 IU daily in achieving optimal serum 25-hydroxyvitamin D (25OHD) concentrations. Optimal 25OHD serum level calculated to be 63.8 nmol/L. All parameters of muscle strength improved fol...See full text at original site
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引用元:
https://doi.org/10.1007/s00198-012-1944-7

データ提供:米国国立医学図書館(NLM)

Vitamin D Deficiency: A Desert of Low Bone Strength

The study delves into the world of vitamin D deficiency, a prevalent issue that can impact bone health and overall well-being. The researchers investigated the effectiveness of different doses of oral cholecalciferol, a form of vitamin D, in patients with confirmed deficiency. They compared the effects of two dosages, 2,000 IU and 5,000 IU, over a three-month period. The study found that a higher dose of 5,000 IU daily was more effective in achieving optimal serum 25-hydroxyvitamin D concentrations. This means that patients receiving the higher dose had improved vitamin D levels in their blood, a crucial factor for strong bones and overall health. This discovery has significant implications for treating vitamin D deficiency and optimizing bone health.

Higher Dose, Stronger Bones

The results indicate that a higher dose of vitamin D is more effective in correcting vitamin D deficiency. Imagine a camel traversing a desert - the higher the water intake, the greater the likelihood of reaching the oasis, just like a higher dose of vitamin D allows for a more robust journey towards optimal bone health.

Embrace the Sunshine, But Don't Forget Your Supplements

While sun exposure is an excellent source of vitamin D, this study reminds us that supplements can play a crucial role in achieving optimal levels, especially for individuals with deficiency. It's like carrying a water pouch in your pack while crossing the desert - it provides a safety net for a successful journey.

Dr.Camel's Conclusion

This research suggests that a higher dose of vitamin D is more effective in treating deficiency. While sun exposure is important, consider supplementing if needed to ensure healthy bone strength.

Date :
  1. Date Completed 2013-08-13
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

22422304

DOI: Digital Object Identifier

10.1007/s00198-012-1944-7

SNS
PICO Info
in preparation
Languages

English

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