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Pharmacokinetics and repolarization effects of intravenous and transdermal granisetron.
Author: DonachiePeter, HowellJulian, MasonJay W, MoonThomas E, O'MahonyBridget, SelnessDaniel S
Original Abstract of the Article :
The need for greater clarity about the effects of 5-HT(3) receptor antagonists on cardiac repolarization is apparent in the changing product labeling across this therapeutic class. This study assessed the repolarization effects of granisetron, a 5-HT(3) receptor antagonist antiemetic, administered i...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1158/1078-0432.CCR-11-2785
データ提供:米国国立医学図書館(NLM)
Investigating the Cardiac Effects of Granisetron: A Journey into the Heart of Antiemetic Therapy
Granisetron, a medication used to prevent nausea and vomiting, is often administered to patients undergoing chemotherapy or surgery. This study, like a careful cartographer mapping the intricacies of a desert ecosystem, investigates the cardiac effects of granisetron when administered intravenously or through a transdermal system.
Navigating the Cardiac Landscape
The study assessed the repolarization effects of granisetron, a crucial aspect of heart function. This is like examining the delicate balance of sand and water that creates a stable dune system. The researchers sought to understand how granisetron affects this vital process, ensuring its safe use in patients.
A Deeper Understanding of Antiemetic Therapy
This research provides valuable insights into the cardiac safety profile of granisetron. It is like gaining a deeper understanding of the delicate ecosystem within a desert, allowing us to navigate this complex landscape with greater knowledge and care.
Dr.Camel's Conclusion
This study, like a cautious camel traversing a sandy terrain, examines the cardiac effects of granisetron, providing valuable information for clinicians and patients alike. By carefully assessing the potential risks and benefits of this medication, we can ensure its safe and effective use.
Date :
- Date Completed 2012-11-05
- Date Revised 2022-03-18
Further Info :
Related Literature
English
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