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The effects of lithium on renal function in older adults--a systematic review.

Author: HerrmannNathan, RejSoham, ShulmanKenneth

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study reviewed the effects of lithium on kidney function in older adults. The results showed that chronic lithium use can lead to chronic renal failure (CRF) and nephrogenic diabetes insipidus (NDI). While acute renal failure (ARF) has been described in lithium intoxication, there is currently no compelling evidence to suggest that lithium should be avoided in elderly patients for fear of renal side effects.
Paper Details　
Original Abstract of the Article :
Chronic renal failure (CRF) and nephrogenic diabetes insipidus (NDI) are potential consequences of chronic lithium use, while acute renal failure (ARF) has been described in lithium intoxication. We performed a systematic review of all studies pertaining to the effects of lithium on the kidney in ol...See full text at original site
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引用元：
https://doi.org/10.1177/0891988712436690

データ提供：米国国立医学図書館（NLM）

Lithium and Renal Function in Older Adults: A Balancing Act

Lithium, a commonly used medication for bipolar disorder, has been associated with potential renal side effects. This systematic review examined the effects of lithium on renal function in older adults, focusing on the incidence of acute renal failure (ARF), chronic renal failure (CRF), and nephrogenic diabetes insipidus (NDI). The review found that while lithium can increase the risk of these renal complications, the overall evidence does not suggest that lithium should be avoided in older adults.

Navigating the Risks and Benefits of Lithium Therapy

This review underscores the importance of carefully considering the potential risks and benefits of lithium therapy in older adults. While lithium can be an effective treatment for bipolar disorder, it's essential to monitor renal function closely and manage potential side effects to ensure patient safety. It's like a camel navigating a desert, aware of the potential dangers while also appreciating the benefits of its journey.

Managing Lithium Therapy for Optimal Outcomes

The review encourages a balanced approach to lithium therapy in older adults, prioritizing patient safety and effective management of potential renal side effects. This approach requires close monitoring of renal function, prompt intervention when necessary, and careful consideration of potential risk factors. It's like a camel navigating the desert, using its knowledge of the terrain to anticipate challenges and adjust its course accordingly.

Dr.Camel's Conclusion

The desert of medicine, like the vast expanse of the Sahara, is filled with both opportunities and challenges. This review sheds light on the potential renal side effects of lithium therapy in older adults, emphasizing the importance of careful monitoring and management to ensure patient safety. It's a reminder that even in the face of complex medical situations, we can find ways to mitigate risks and maximize benefits, ultimately achieving positive outcomes for those in our care.
Date :
  1. Date Completed 2012-08-17
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

22467847

DOI: Digital Object Identifier

10.1177/0891988712436690

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