Addition of pregabalin to multimodal analgesic therapy following ankle surgery: a randomized double-blind, placebo-controlled trial.

Author: BuschiazzoValeria L, Jules-ElyseeKethy M, KahnRichard L, LasalaVincent R, LevineDavid S, LinEdward, LiuSpencer S, ParoliLeonardo, PowellKarlyn, RobertsMatthew M, WukovitsBarbara, YadeauJacques T

Paper Details 
Original Abstract of the Article :
Pregabalin is often used as a perioperative analgesic adjunct; some studies show benefit, but others do not. Adverse effects, such as confusion and sedation, have been attributed to perioperative use of pregabalin. We tested the hypothesis that pregabalin, when used as part of a multimodal analgesic...See full text at original site
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引用元:
https://doi.org/10.1097/AAP.0b013e31824c6846

データ提供:米国国立医学図書館(NLM)

A Multimodal Approach to Pain Relief: Pregabalin and Ankle Surgery

This randomized controlled trial investigates the effectiveness of pregabalin, a medication commonly used to manage pain, as a perioperative analgesic adjunct following ankle surgery. The study explores the potential benefits and risks of pregabalin in a multimodal analgesic regimen, seeking to improve pain control and minimize adverse effects.

Navigating the Shifting Sands of Pain Management: Pregabalin's Role

The research shows that pregabalin, when used as part of a multimodal analgesic regimen, can effectively reduce the duration of moderate to severe pain in the first 24 hours following ankle surgery. However, the study also notes the potential for adverse effects, such as confusion and sedation, highlighting the importance of careful monitoring and individualized dosing strategies.

A Journey Through the Oasis of Effective Pain Relief: A Multimodal Approach

The study emphasizes the importance of a multimodal approach to pain management, considering a combination of different medications and therapies to optimize pain control and minimize adverse effects. It encourages healthcare professionals to carefully assess individual patient needs and tailor treatment plans to achieve the best possible outcomes.

Dr.Camel's Conclusion

This research offers valuable insights into the potential benefits and risks of using pregabalin as a perioperative analgesic adjunct for ankle surgery. The findings suggest that pregabalin, when carefully incorporated into a multimodal approach, can effectively manage pain, but vigilance is crucial to monitor for potential adverse effects and ensure individual patient safety. This study highlights the importance of personalized pain management strategies, navigating the desert of pain and maximizing the benefits of multimodal approaches to achieve optimal pain relief.

Date :
  1. Date Completed 2012-08-21
  2. Date Revised 2019-01-09
Further Info :

Pubmed ID

22476240

DOI: Digital Object Identifier

10.1097/AAP.0b013e31824c6846

Related Literature

SNS
PICO Info
in preparation
Languages

English

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