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Effects of estrogens on sleep and psychological state of hypogonadal women.

Author: RegesteinQ, RyanK J, SchiffI, TulchinskyD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Conjugated estrogens lowered gonadotropin levels and reduced vasomotor flushes in hypogonadal women. Estrogen administration was associated with shorter sleep latency and longer rapid eye movement sleep. Psychological testing showed that estrogens led to less outward aggression but more inward hostility.
Paper Details　
Original Abstract of the Article :
A double-lind crossover study involving 16 hypogonadal women compared the effects of placebo and conjugated estrogens, 0.625 mg daily, on gonadotropin levels, symptoms, sleep patterns, and psychological state. After one month, serum concentrations of follicle-stimulating hormone fell 31%, and levels...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/226735

データ提供：米国国立医学図書館（NLM）

Estrogen: A Balancing Act for Women's Health

This research investigates the effects of [estrogens] on the [sleep] and [psychological state] of [hypogonadal women]. The study uses a [double-blind crossover design] to compare the effects of [placebo] and [conjugated estrogens] on [gonadotropin levels], [symptoms], [sleep patterns], and [psychological state] in a group of [hypogonadal women].

Estrogen: A Potential Sleep and Mood Booster

The study reveals that [estrogens] can have a positive impact on [sleep], reducing [sleep latency] and increasing [rapid eye movement (REM) sleep]. However, the study also found that [estrogens] can influence [psychological state], potentially increasing [inner hostility] while decreasing [outward aggression].

Women's Health: A Holistic Approach

This study emphasizes the importance of considering the [holistic] impact of [hormonal] treatments on [women's health]. It's essential to work closely with a [healthcare professional] to weigh the potential [benefits] and [risks] of [estrogen] therapy based on individual needs and risk factors.

Dr. Camel's Conclusion

This study explores the complex interplay between [estrogens], [sleep], and [psychological state] in [hypogonadal women]. While [estrogen] therapy can offer benefits for specific symptoms, it's essential to approach it with a balanced understanding of both its potential benefits and risks. It's like navigating a desert landscape – sometimes, the path forward requires a careful balance of both the beauty and challenges that lie ahead.

Date :
  1. Date Completed 1979-12-29
  2. Date Revised 2016-10-17
Further Info :

Pubmed ID

226735

DOI: Digital Object Identifier

226735

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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