Oral administration of forskolin and rutin contributes to intraocular pressure control in primary open angle glaucoma patients under maximum tolerated medical therapy.

Author: BrusiniPaolo, CentofantiMarco, CiancagliniMarco, IesterMichele, RossettiLuca M, RussoVincenzo, UvaMaurizio G, VetrugnoMichele

Paper Details 
Original Abstract of the Article :
Tight control of intraocular pressure (IOP) is still the only therapeutic approach available for the treatment of primary open angle glaucoma (POAG). However, some patients do not respond adequately to hypotonising drugs, and despite multiple drug combinations they cannot reach their target IOP. For...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1089/jop.2012.0021

データ提供:米国国立医学図書館(NLM)

Forskolin and Rutin: A Potential Duo for Intraocular Pressure Control in Glaucoma

Glaucoma, a leading cause of irreversible blindness, requires careful management of intraocular pressure (IOP). This research, a journey through the desert of ophthalmological treatments, investigates the potential of forskolin and rutin in controlling IOP in patients with primary open angle glaucoma (POAG).

A Novel Approach: Combining Natural Compounds

Researchers explored the combined effects of forskolin, a natural compound with known IOP-reducing properties, and rutin, a flavonoid with antioxidant properties. This study, like a meticulous exploration of desert herbs, sought to identify synergistic effects that could enhance IOP control.

Promising Results: A Glimpse of Hope

The study revealed a significant reduction in IOP in POAG patients who received oral forskolin and rutin, even those who had not responded adequately to conventional medications. This finding suggests that these natural compounds may offer a promising alternative or adjunct therapy for managing IOP in glaucoma.

Health Implications and Everyday Life: A Path to Vision Preservation

This research, a beacon of hope in the desert of glaucoma management, suggests that forskolin and rutin may offer a potential new approach to controlling IOP. For individuals with glaucoma, this research provides a glimmer of optimism for preserving vision and maintaining a healthy lifestyle.

Dr. Camel's Conclusion

This research, a compelling exploration in the desert of glaucoma management, highlights the potential of forskolin and rutin as a natural duo for controlling IOP. The findings suggest that these compounds may offer a promising alternative or adjunct therapy for managing glaucoma, providing a potential path towards vision preservation.

Date :
  1. Date Completed 2013-02-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22731245

DOI: Digital Object Identifier

10.1089/jop.2012.0021

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.