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Rectal paracetamol in newborn infants after assisted vaginal delivery may increase pain response.
Author: BucherHans Ulrich, BurkhardtTilo, BührerChristoph, HoesliIrene, JostKerstin, KrafftAlexander, NelleMathias, SchöbiNina, SurbekDaniel, TinnerEva Maria, Ulrich MeggedYvonne
Original Abstract of the Article :
OBJECTIVE: To assess the efficacy of paracetamol (acetaminophen) for neonatal pain relief. STUDY DESIGN: Randomized, double-blind placebo-controlled trial in 3 Swiss university hospitals. Term and near-term infants (n = 123) delivered by forceps or vacuum were randomized to receive 2 suppositories ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jpeds.2012.06.020
データ提供:米国国立医学図書館(NLM)
Paracetamol: A Double-Edged Sword for Newborn Pain Relief
Neonatal pain management is a sensitive and complex topic, and this study explores the use of paracetamol (acetaminophen) for pain relief in newborn infants after assisted vaginal delivery. The authors conducted a randomized, double-blind placebo-controlled trial to assess the efficacy and potential risks of rectal paracetamol in this population.
Paracetamol's Complex Effects on Newborns
The study found that paracetamol did not significantly reduce pain scores immediately after birth but unexpectedly increased the pain response to a heel prick for metabolic screening at days 2-3 of life. This suggests that paracetamol may not be effective for immediate pain relief in newborns and may even increase their sensitivity to pain later on. It's like navigating a desert with a guide - what seems helpful at first might have unintended consequences later.
A Cautious Approach to Neonatal Pain Relief
This study highlights the need for caution when using paracetamol for pain relief in newborns. It emphasizes the importance of considering the potential risks and benefits of analgesics in this population and exploring alternative pain management strategies. Remember, the desert of neonatal care requires a delicate touch and careful consideration of all factors before choosing a path to recovery.
Dr. Camel's Conclusion
This study underscores the complexities of pain management in newborns. While paracetamol may offer some benefits, it's crucial to be aware of its potential to increase pain sensitivity later on. It's a reminder that the desert of neonatal care requires a thoughtful approach, balancing the needs of the child with the latest scientific evidence.
Date :
- Date Completed 2013-02-19
- Date Revised 2022-03-31
Further Info :
Related Literature
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