Paper Details
- Home
- Paper Details
A randomized controlled trial assessing the effects of raltegravir intensification on endothelial function in treated HIV infection.
Author: BuschMichael P, DeeksSteven G, HarvillKara, HatanoHiroyu, HohRebecca, HsuePriscilla Y, MakaKristinalisa, MartinJeffrey N, PalmerSarah, ScherzerRebecca, SinclairElizabeth, WuYuaner
Original Abstract of the Article :
OBJECTIVES: To determine whether intensification with raltegravir improves endothelial function in antiretroviral-treated HIV-infected individuals. DESIGN: : Randomized, double-blinded, placebo-controlled study. METHODS: Fifty-six subjects with treatment-mediated viral suppression for at least 1 y...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/22918156
データ提供:米国国立医学図書館(NLM)
Investigating the Effects of Raltegravir Intensification on Endothelial Function in HIV-Infected Individuals
This study explores the important area of [HIV/AIDS] research by investigating the potential benefits of raltegravir intensification on endothelial function in individuals with treated HIV infection. The authors, driven by the need to better understand the cardiovascular risks associated with HIV treatment, conducted a randomized, double-blinded, placebo-controlled study to assess the impact of raltegravir intensification on endothelial function. Their findings provide valuable insights into the potential cardiovascular implications of raltegravir therapy.
Raltegravir Intensification: No Significant Impact on Endothelial Function
The study found no significant differences in endothelial function between the raltegravir intensification group and the placebo group. This finding suggests that adding raltegravir to suppressive antiretroviral therapy does not appear to have a major negative impact on cardiovascular risk, at least as measured by endothelial function. While this is a promising finding, it's crucial to note that the study was limited in its duration and scope.
Managing Cardiovascular Risk in HIV-Infected Individuals
This research highlights the importance of carefully considering the potential cardiovascular risks associated with HIV treatment. While the study found no significant negative impact of raltegravir intensification on endothelial function, it's essential to remain vigilant and conduct further research to gain a more comprehensive understanding of the long-term cardiovascular implications of antiretroviral therapy. This knowledge could empower clinicians to make informed decisions about treatment options, minimizing cardiovascular risk and optimizing patient outcomes.
Dr.Camel's Conclusion
This research, like a camel navigating a challenging desert landscape, investigates the effects of raltegravir intensification on endothelial function in HIV-infected individuals. It reveals that raltegravir intensification does not appear to have a significant negative impact on cardiovascular risk, at least as measured by endothelial function. This study, like a refreshing oasis in the desert, provides valuable insights into the potential cardiovascular implications of HIV treatment, highlighting the importance of careful monitoring and further research in this area.
Date :
- Date Completed 2013-01-04
- Date Revised 2021-10-21
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.