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Bile acid binding resin improves metabolic control through the induction of energy expenditure.

Author: AritaEri, AuwerxJohan, HoraiYasushi, HoutenSander M, ItohHiroshi, Kaneko-IwasakiNao, MatakiChikage, MorimotoKohkichi, MurahashiKarin, SatoHiroyuki, SchoonjansKristina, SugizakiTaichi, SuzukiTatsuya, WatanabeMitsuhiro

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Bile acids play a role in both lipid metabolism and cell signaling. This abstract discusses how bile acid binding resins (BABRs) can improve glucose tolerance and insulin resistance in models of diet-induced obesity.
Paper Details　
Original Abstract of the Article :
Besides well-established roles of bile acids (BA) in dietary lipid absorption and cholesterol homeostasis, it has recently become clear that BA is also a biological signaling molecule. We have shown that strategies aimed at activating TGR5 by increasing the BA pool size with BA administration may co...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430641/

データ提供：米国国立医学図書館（NLM）

Bile Acid Binding Resin: A New Path to Metabolic Control

This research delves into the intricate world of bile acids (BAs), exploring their role in lipid absorption, cholesterol homeostasis, and metabolic health. It's like a desert oasis, where water plays a crucial role in maintaining life. The study investigates how bile acid binding resin (BABR) can improve metabolic control by affecting energy expenditure.

Unraveling the Mechanisms of BABR

The authors highlight the established role of BABR in reducing cholesterol levels, but delve deeper into its potential to improve glucose tolerance and insulin resistance. They explore the mechanisms by which BABR affects glycemic control in diet-induced obesity models, uncovering a potential pathway for improving metabolic health. It's like discovering a hidden spring in the desert, revealing a source of energy and vitality.

Navigating the Desert of Metabolic Disorders

This study provides a promising glimpse into the potential of BABR as a therapeutic agent for managing metabolic disorders. It emphasizes the need for further research to fully understand the mechanisms of BABR's action and explore its potential as a tool for combating metabolic syndrome. It's like finding a new route through the desert, offering a path toward better health and well-being.

Dr.Camel's Conclusion

This study highlights the potential of BABR as a therapeutic agent for managing metabolic disorders, suggesting that further research into its mechanisms and effectiveness could provide a valuable oasis for those struggling with these conditions.

Date :
  1. Date Completed 2013-02-19
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22952571

DOI: Digital Object Identifier

PMC3430641

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Languages

English

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