Efficacy of a modified sequential therapy including bismuth subcitrate as first-line therapy to eradicate Helicobacter pylori in a Turkish population.

Author: BagciSait, EmerOzdes, ErçinCemal Nuri, GençHalil, GunalArmagan, KadayifçiAbdurrahman, OzelA Melih, PolatZulfikar, SakinYusuf Serdar, SivriBulent, UygunAhmet, Uygur-BayramiçliOya, ÇelebiGürkan

Paper Details 
Original Abstract of the Article :
BACKGROUND: Eradication rates of Helicobacter pylori with standard triple therapy are not satisfactory. Sequential therapy is an alternative method to overcome this problem. OBJECTIVES: The aim of this study was to assess efficacy of a modified sequential therapy with the addition of a bismuth prep...See full text at original site
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引用元:
https://doi.org/10.1111/j.1523-5378.2012.00989.x

データ提供:米国国立医学図書館(NLM)

Eradicating Helicobacter pylori: A Quest for Effective Treatment

The battle against [Helicobacter pylori] infection is an ongoing one, with researchers striving to develop effective eradication therapies. This study explores the efficacy of a [modified sequential therapy] incorporating [bismuth subcitrate] as a first-line treatment in a Turkish population. The researchers assessed the eradication rates of H. pylori using the [urea breath test (UBT)] after completion of the 14-day treatment regimen.

Modified Sequential Therapy: A Promising Approach for H. pylori Eradication

The study demonstrates a high eradication rate of H. pylori using the modified sequential therapy, with both per-protocol and intention-to-treat analyses yielding promising results. The findings suggest that this treatment strategy may be an effective option for managing H. pylori infection, particularly in populations where standard triple therapy has shown limited success.

Optimizing H. pylori Treatment: Balancing Efficacy and Tolerability

The study highlights the importance of finding a balance between treatment efficacy and tolerability. While the modified sequential therapy demonstrates high eradication rates, it's essential to consider potential side effects and individual patient factors to ensure safe and effective treatment.

Dr.Camel's Conclusion

Just like a camel seeking a source of water in a barren desert, we must seek effective treatments for H. pylori infection. This study provides encouraging results for a modified sequential therapy incorporating bismuth, offering a promising approach for combating this prevalent infection. By continuing to explore new therapeutic strategies and understanding patient-specific factors, we can strive for optimal treatment outcomes and improve the health of individuals affected by H. pylori infection.

Date :
  1. Date Completed 2013-03-12
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

23067136

DOI: Digital Object Identifier

10.1111/j.1523-5378.2012.00989.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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