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Phase II study of glucosamine with chondroitin on aromatase inhibitor-associated joint symptoms in women with breast cancer.
Author: BrafmanLois, CrewKatherine D, GreenleeHeather, HershmanDawn L, InselBeverly, KalinskyKevin, KranwinkelGrace, MaurerMatthew, ShaoTheresa, TsaiWei Yann
Original Abstract of the Article :
PURPOSE: Many women with hormone receptor-positive breast cancer discontinue effective aromatase inhibitor (AI) treatment due to joint symptoms. METHODS: We conducted a single-arm, open-label, phase II study evaluating glucosamine-sulfate (1,500 mg/day) + chondroitin-sulfate (1,200 mg/day) for 24 w...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/23111941
データ提供:米国国立医学図書館(NLM)
Glucosamine and Chondroitin: A Potential Relief for Aromatase Inhibitor-Associated Joint Symptoms
Aromatase inhibitors (AIs), a vital tool in the treatment of hormone receptor-positive breast cancer, can sometimes cause unpleasant joint symptoms. This research, a journey through the desert of breast cancer treatment side effects, investigates the potential benefits of glucosamine and chondroitin in alleviating these joint symptoms. The researchers conducted a phase II study, evaluating the effectiveness of glucosamine and chondroitin in reducing joint pain and stiffness in women with breast cancer who had developed these symptoms after initiating AI therapy. Their findings offer promising insights into the potential of these supplements for managing AI-associated joint discomfort.
A Ray of Hope for AI-Associated Joint Symptoms
This study, a beacon of light in the desert of breast cancer treatment side effects, suggests that glucosamine and chondroitin may provide relief for AI-associated joint symptoms. The researchers found that a significant proportion of patients experienced improvement in joint pain and stiffness, suggesting the potential of these supplements to enhance comfort and quality of life for women undergoing AI therapy. This research encourages further investigation into the efficacy of glucosamine and chondroitin in managing these side effects and potentially improving adherence to AI treatment.
Navigating the Desert of Breast Cancer Treatment Side Effects
This research highlights the importance of addressing the side effects of breast cancer treatment, such as AI-associated joint symptoms. The study suggests that glucosamine and chondroitin may offer a potential solution for managing these side effects, potentially improving patient comfort and quality of life. This research encourages us to explore innovative approaches to manage treatment side effects, seeking to minimize discomfort and enhance the overall well-being of our patients.
Dr. Camel's Conclusion
This study offers a glimmer of hope for women with breast cancer experiencing joint symptoms associated with aromatase inhibitor therapy. The research suggests that glucosamine and chondroitin may provide relief from these side effects, potentially improving patient comfort and adherence to treatment. This study reminds us that the desert of breast cancer treatment is vast and complex, and we must continue to seek ways to improve the lives of our patients by addressing both the disease and its side effects.
Date :
- Date Completed 2013-09-17
- Date Revised 2022-03-09
Further Info :
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