Paper Details

  1. Home
  2. Paper Details

Novel approaches to corticosteroid treatment in Duchenne muscular dystrophy.

Author: BushbyKate, ConnorEdward M, DamskerJesse, HoffmanEric P, McCallJohn M, NagarajuKanneboyina, ReevesErica

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Prednisone is a medication that is sometimes used to treat Duchenne muscular dystrophy (DMD), a genetic disorder that causes muscle weakness. This study reviewed the use of prednisone in DMD and highlighted the need for optimizing the type and dosage of glucocorticoids to maximize efficacy and minimize side effects.
Paper Details　
Original Abstract of the Article :
Although prednisone has never been formally approved for use in Duchenne muscular dystrophy (DMD) by regulatory agencies, its efficacy has been confirmed in trials dating from the 1980s. There is a strong need for optimization of both specific type of glucocorticoid (eg, prednisone, vs deflazacort o...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/23137739

データ提供：米国国立医学図書館（NLM）

Corticosteroid Treatment in Duchenne Muscular Dystrophy: Navigating a Complex Landscape

Duchenne muscular dystrophy (DMD), a debilitating genetic condition, can feel like a relentless sandstorm, slowly eroding strength and mobility. This study explores the use of corticosteroids in DMD, highlighting the need for optimizing treatment strategies to maximize benefits while minimizing side effects.

Corticosteroids: A Balancing Act

The study emphasizes the need for careful consideration of corticosteroid type and dosage regimen in DMD treatment. Just as a skilled camel driver navigates a shifting desert landscape, so too do clinicians strive to find the optimal balance between efficacy and safety in corticosteroid therapy.

A Path to Progress: Optimizing Corticosteroid Treatment

This research highlights the importance of ongoing research to optimize corticosteroid treatment for DMD, exploring new options and refining existing strategies. The study's findings suggest that a more personalized approach to corticosteroid therapy could lead to improved outcomes and a better quality of life for individuals with DMD.

Dr.Camel's Conclusion

This study explores the complex world of corticosteroid treatment for Duchenne muscular dystrophy, emphasizing the need for careful optimization to maximize benefits while minimizing side effects. Just as a camel navigates a challenging desert, so too do individuals with DMD and their healthcare providers seek the most effective and safe treatment options.

Date :
  1. Date Completed 2013-05-22
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

23137739

DOI: Digital Object Identifier

NIHMS429373

Related Literature

Article Analysis
・Side Effects of deflazacort
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.