Paper Details

  1. Home
  2. Paper Details

Synergistic antivirus effect of combined administration of Combivir with Angelica polysaccharide sulfate.

Author: ChengYing, HuangJunjie, JiaMin, MeiQibing, YangTiehong, YueZhenggang, ZhangXinxin, ZhouSiyuan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the synergistic effect of Anglica polysaccharide sulfate (APS-1) and Combivir, an anti-AIDS drug, on murine leukemia virus in vivo. The results show that the combination of APS-1 and Combivir significantly decreased virus replication and enhanced CD4(+) cell percentage and CD4(+)/CD8(+) ratio.
Paper Details　
Original Abstract of the Article :
This study is to investigate the synergistic effect of Anglica polysaccharide sulfate (APS-1) and Combivir, an anti-AIDS drug, on murine leukemia virus in vivo. As the results shown, the virus replication was significantly decreased by the combination of APS-1 and Combivir, which tended to be furthe...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.ijbiomac.2012.11.006

データ提供：米国国立医学図書館（NLM）

A Powerful Alliance: Combivir and APS-1

This study takes us into the fascinating world of virology, specifically exploring the fight against the Murine Leukemia Virus (MLV), a viral desert that can be difficult to conquer. Our study investigated the synergistic effect of a combination of Combivir, a drug used to fight AIDS, and Angelica polysaccharide sulfate (APS-1) against MLV.

Our research revealed that APS-1, like a skilled desert guide, enhances the effectiveness of Combivir against MLV, reducing viral replication and promoting immune cell recovery. This is similar to having a guide who knows the best routes and resources to overcome the challenges of a desert journey. APS-1 also helped mitigate the toxicity of Combivir, further increasing its effectiveness.

Combivir and APS-1: A Powerful Partnership

This study shows the potential of combining APS-1 with Combivir as a powerful new approach to fighting MLV. This combined therapy offers a more efficient and potentially safer treatment option, like having a camel that can carry both food and water in the desert.

Navigating the Viral Desert

Our study demonstrates the importance of exploring synergistic therapies to combat the challenges of viral diseases. The combination of APS-1 and Combivir could potentially offer a safer and more effective treatment option for MLV, providing a valuable oasis in the fight against this challenging viral desert.

Dr.Camel's Conclusion

This study is like a compass leading us to new pathways in the fight against viral diseases. The synergistic effects of APS-1 and Combivir offer a promising approach to combating MLV, demonstrating the power of teamwork and innovation in conquering the challenging deserts of viral infections.

Date :
  1. Date Completed 2013-06-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

23153762

DOI: Digital Object Identifier

10.1016/j.ijbiomac.2012.11.006

Related Literature

Article Analysis
・Effects of lamivudine and zidovudine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.