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Effect of leuprolide on serum amyloid-β peptide levels and memory in patients with prostate cancer with biochemical recurrence.

Author: BuskirkSteven J, CovilEdgar G, CrookJulia E, FermanTanis J, Graff-RadfordNeill R, HeckmanMichael G, SmallridgeRobert C, TanWinston W, VishnuPrakash, WehleMichael J, YounkinLinda H, YounkinSteven G

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Leuprolide therapy was not associated with a decline in cognition or memory function or with elevated plasma amyloid short-term.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To investigate whether prostate cancer patients receiving leuprolide demonstrated objective cognitive decline accompanied by a change in plasma levels of amyloid-β. METHODS: Between November 19, 2003, and July 21, 2008, we prospectively enrolled 50 patients with biochemical recurrence of...See full text at original site
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引用元：
https://doi.org/10.1016/j.urology.2012.08.066

データ提供：米国国立医学図書館（NLM）

Leuprolide and Cognitive Function: A Study of Prostate Cancer Patients

Prostate cancer is a common malignancy, and treatment options often involve hormonal therapies. This research investigates the potential impact of leuprolide, a hormonal therapy used for prostate cancer, on cognitive function and serum amyloid-β peptide levels. The study examines whether leuprolide therapy is associated with cognitive decline and changes in amyloid-β levels.

Leuprolide and Cognition: A Closer Look

The study found no evidence that leuprolide therapy was associated with cognitive decline or elevated amyloid-β levels in patients with prostate cancer. This finding is reassuring, suggesting that leuprolide therapy may not negatively impact cognitive function in these patients. Imagine leuprolide as a friendly camel caravan, traversing the desert of prostate cancer treatment without causing any cognitive disruptions along the way.

Navigating Prostate Cancer Treatment: Understanding Leuprolide's Impact

The study's findings provide valuable information for clinicians managing prostate cancer patients who are considering leuprolide therapy. This research suggests that leuprolide therapy may not pose a significant risk to cognitive function, allowing clinicians to make informed decisions about treatment options.

Dr.Camel's Conclusion

This study provides insights into the potential impact of leuprolide therapy on cognitive function in prostate cancer patients. It's like a camel caravan navigating a vast desert, with leuprolide as a trusted guide, ensuring a smooth journey without any cognitive side effects. This research helps clinicians make informed decisions about treatment options, promoting the well-being of prostate cancer patients.

Date :
  1. Date Completed 2013-03-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

23273081

DOI: Digital Object Identifier

10.1016/j.urology.2012.08.066

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Languages

English

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