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Clinical, safety, and economic evidence in radioactive iodine-refractory differentiated thyroid cancer: a systematic literature review.

Author: AndersonRoger T, KeatingKaren, LinnehanJohn E, TongbramVanita, WirthLori J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study examines potential treatments for differentiated thyroid cancer (DTC) that has become resistant to radioactive iodine (RAI), a common treatment for this type of cancer. The review focuses on clinical trials of novel targeted therapies and evaluates their effectiveness, safety, and cost.
Paper Details　
Original Abstract of the Article :
Thyroid cancer is the most common endocrine malignancy, with differentiated thyroid cancer (DTC) comprising ~93% of all thyroid cancers. While most cases of DTC are curable with the use of surgery and radioactive iodine (RAI) ablation of the remaining thyroid remnant, prognosis is dire and treatment...See full text at original site
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引用元：
https://doi.org/10.1089/thy.2012.0520

データ提供：米国国立医学図書館（NLM）

Radioactive Iodine-Refractory DTC: A Challenging Terrain

This study takes us on a journey into the world of thyroid cancer, exploring the challenges associated with radioactive iodine-refractory differentiated thyroid cancer (RAI-R DTC). The researchers, like seasoned oncologists, delve into the complexities of this difficult-to-treat condition, seeking to identify potential treatment options and improve outcomes for patients. The study, like a comprehensive medical journal, provides a valuable overview of the challenges and opportunities in managing RAI-R DTC.

Navigating a Difficult Path: Seeking Solutions for RAI-R DTC

The study highlights the urgent need for effective treatment options for RAI-R DTC, a condition that can be as challenging to manage as navigating a treacherous desert. The researchers, like tireless explorers, meticulously review the existing scientific literature to identify promising therapeutic strategies, seeking to improve outcomes for patients facing this difficult diagnosis. This comprehensive review, like a well-stocked caravan, provides valuable insights into the current landscape of RAI-R DTC treatment.

A Glimmer of Hope in the Desert

This study, like a shimmering oasis in the desert, offers hope for patients with RAI-R DTC. The researchers, like optimistic explorers, highlight the ongoing research efforts to develop novel targeted therapies, providing a glimmer of hope for patients facing this challenging diagnosis. This exploration of potential treatment options, like a well-charted map, guides us toward a brighter future for individuals with RAI-R DTC.

Dr.Camel's Conclusion

This study, like a beacon in the desert, sheds light on the ongoing efforts to improve treatment outcomes for patients with radioactive iodine-refractory differentiated thyroid cancer (RAI-R DTC). The researchers' comprehensive review underscores the urgent need for effective treatment options and highlights the promising potential of novel targeted therapies in managing this challenging condition.
Date :
  1. Date Completed 2013-09-19
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

23294230

DOI: Digital Object Identifier

10.1089/thy.2012.0520

SNS
PICO Info
in preparation
Languages

English

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