A contemporary update on rates and management of toxicities of targeted therapies for metastatic renal cell carcinoma.

Author: AlaskerAhmed, BianchiMarco, HannaNawar, HansenJens, IsmailSalima, KarakiewiczPierre I, MeskawiMalek, PerrottePaul, SunMaxine, TianZhe

Paper Details 
Original Abstract of the Article :
BACKGROUND: To provide an updated review of adverse events associated with sunitinib, pazopanib, bevacizumab, temsirolimus, axitinib, everolimus and sorafenib and their management. MATERIALS AND METHODS: We performed a PubMed and Cochrane-based review of side effects associated with the seven agent...See full text at original site
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引用元:
https://doi.org/10.1016/j.ctrv.2012.12.006

データ提供:米国国立医学図書館(NLM)

Navigating the Side Effects of Targeted Therapies for Metastatic Renal Cell Carcinoma

The field of [oncology] is constantly evolving, seeking to develop more effective and targeted therapies for cancer. This research focuses on the [toxicities] associated with [targeted therapies] used in the treatment of [metastatic renal cell carcinoma (mRCC)]. The authors provide a comprehensive overview of the adverse events associated with seven common targeted therapies, including [sunitinib, pazopanib, bevacizumab, temsirolimus, axitinib, everolimus, and sorafenib]. They emphasize the importance of [prevention, early recognition, and prompt management] of these side effects, much like a seasoned desert traveler who knows how to identify and avoid potential dangers. The research provides guidance for clinicians on how to minimize the risks associated with these powerful drugs, ensuring that patients can benefit from their therapeutic effects without experiencing excessive side effects.

Managing Side Effects: A Guide for the Desert Traveler

This research serves as a valuable guide for clinicians and patients navigating the complex landscape of mRCC treatment. It highlights the importance of careful monitoring and proactive management of side effects, ensuring that patients receive the optimal benefit from targeted therapies while minimizing the risks. It's like having a trusty map and compass when navigating a desert; it provides guidance and helps us avoid treacherous paths.

Minimizing Risks in the Desert of Cancer Treatment

The research underscores the need for a collaborative approach to managing mRCC, involving both clinicians and patients in the decision-making process. By being aware of the potential side effects and actively participating in their management, patients can play a vital role in ensuring the success of their treatment. It's like traversing a vast and challenging desert; by working together, we can navigate the difficult terrain and achieve our goals.

Dr.Camel's Conclusion

This comprehensive review provides invaluable insights for clinicians and patients navigating the complexities of mRCC treatment. It's like having a well-stocked caravan for a long journey; by being prepared and aware of the challenges, we can confidently traverse the desert of cancer treatment and reach our destination.

Date :
  1. Date Completed 2013-05-10
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

23317510

DOI: Digital Object Identifier

10.1016/j.ctrv.2012.12.006

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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