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Evaluation of ocular hypersensitivity to dipivalyl epinephrine by component eye-drop testing.

Author: EvansR B, HendersonW R, JohnstoneM A, PetersenP E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Dipivefrin, an ingredient in Propine eye drops, was identified as the cause of conjunctivitis in five patients.
Paper Details　
Original Abstract of the Article :
Dipivalyl epinephrine (dipivefrin) is a prodrug of epinephrine used for topical glaucoma therapy. Local side effects have been noted in approximately 20% of patients treated and include conjunctival hyperemia, foreign body sensation, and follicular conjunctivitis. We studied five patients with adver...See full text at original site
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引用元：
https://doi.org/10.1016/0091-6749(90)90083-g

データ提供：米国国立医学図書館（NLM）

Unveiling the Culprit: Identifying the Cause of Ocular Hypersensitivity

This study delves into the challenging world of ocular hypersensitivity, exploring the causes behind adverse reactions to eye drops. The researchers examined five patients experiencing adverse reactions to dipivalyl epinephrine (dipivefrin), a common treatment for glaucoma. By conducting patch testing and applying individual components of the eye drops to the patients' eyes, the researchers successfully identified dipivalyl epinephrine as the culprit responsible for the patients' reactions.

Pinpointing the Cause: A Step Towards Personalized Ocular Care

This study demonstrates the importance of careful and thorough investigation when treating ocular hypersensitivity. By identifying the specific component causing the reaction, healthcare providers can offer patients more personalized and effective treatments, minimizing the risk of adverse reactions. This research, like a camel expertly navigating a desert landscape, identifies the key factor contributing to the problem, paving the way for a more effective solution.

Personalized Solutions: A Tailored Approach to Ocular Health

This study emphasizes the importance of personalized care in ophthalmology. By conducting thorough testing to identify the specific cause of ocular hypersensitivity, healthcare providers can tailor treatment plans to individual patients, minimizing the risk of adverse reactions and promoting better overall ocular health.

Dr.Camel's Conclusion

This study highlights the importance of careful investigation when addressing ocular hypersensitivity. By identifying the specific component causing the reaction, healthcare providers can provide more personalized and effective treatment, potentially preventing future adverse reactions and promoting better overall ocular health.

Date :
  1. Date Completed 1990-06-07
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

2332569

DOI: Digital Object Identifier

10.1016/0091-6749(90)90083-g

Related Literature

Article Analysis
・Side Effects of dipivefrin ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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