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Long-term effects of metaproterenol in asthmatic children.

Author: MarksM B, SacknerM A, SilvaG, ZuckerC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Oral metaproterenol was administered to asthmatic children for 3 months. No chronic tolerance developed to the drug. The bronchodilating effect of metaproterenol lasted at least 5 hours.
Paper Details　
Original Abstract of the Article :
Oral metaproterenol was administered daily for 3 months to asthmatic children. The study was designed to determine whether chronic tolerance developed to this drug. Initial and final crossovers on the first 2 and the last 2 days of the investigation to a test dose of metaproterenol and placebo faile...See full text at original site
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引用元：
https://doi.org/10.1164/arrd.1977.115.6.945

データ提供：米国国立医学図書館（NLM）

Metaproterenol: A Stable Oasis in the Desert of Asthma

Asthma, a chronic respiratory condition affecting millions, can cause wheezing, coughing, and shortness of breath. This study investigated the long-term effects of metaproterenol, a bronchodilator, in asthmatic children, examining the potential for tolerance to develop over time. The research, conducted over a three-month period, involved daily administration of metaproterenol and frequent assessments of lung function. The findings revealed that metaproterenol effectively provided bronchodilation, improving lung function and respiratory mechanics, without evidence of tolerance development. This research highlights the potential of metaproterenol as a long-term treatment option for asthma, providing relief and improved respiratory function for children.

Exploring the Sands of Asthma Treatment

This research expands our understanding of asthma management, highlighting the potential of metaproterenol as a safe and effective long-term treatment option. It's like navigating the vast desert of asthma research, seeking effective solutions for children struggling with this chronic condition. The findings suggest that metaproterenol can provide long-term relief and improved respiratory function for asthmatic children, empowering them to live active and healthy lives.

Finding Relief in the Desert of Asthma

This research provides valuable insights into the potential of metaproterenol for managing asthma in children. It's like discovering a hidden oasis in the desert of asthma, offering a source of relief and improved respiratory function for children struggling with this chronic condition. The findings suggest that metaproterenol can be a valuable tool in managing asthma, promoting healthy lung function and enabling children to lead active and fulfilling lives.

Dr. Camel's Conclusion

This study highlights the importance of finding effective long-term solutions for managing asthma in children. It's like discovering a hidden oasis in the vast desert of asthma research, providing a source of relief and improved respiratory function for children struggling with this chronic condition. The findings suggest that metaproterenol can be a valuable tool in managing asthma, promoting healthy lung function and enabling children to lead active and fulfilling lives.
Date :
  1. Date Completed 1981-08-27
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

233545

DOI: Digital Object Identifier

10.1164/arrd.1977.115.6.945

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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