Rheohaemapheresis in the treatment of nonvascular age-related macular degeneration.

Author: BlahaM, BlahaV, LangrovaH, LanskaM, RencovaE, RozsivalP, SobotkaL, StudnickaJ

Paper Details 
Original Abstract of the Article :
PURPOSE: To evaluate the experience with rheohaemapheresis (RH) in the treatment of age-related macular degeneration (AMD). METHODS: Thirty-eight patients were each treated with 8 procedures of RH (14 males, 24 females). The control group consisted of 34 random patients (30 females, 4 males) with t...See full text at original site
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引用元:
https://doi.org/10.1016/j.atherosclerosissup.2012.10.023

データ提供:米国国立医学図書館(NLM)

Rheohaemapheresis: A Potential Treatment for Nonvascular Age-Related Macular Degeneration?

The delicate tapestry of vision, particularly the intricate structure of the macula, is often susceptible to age-related degeneration. This study explores the use of rheohaemapheresis (RH), a procedure that involves removing and filtering blood plasma, as a potential treatment for nonvascular age-related macular degeneration (AMD). The researchers conducted a retrospective analysis of 38 patients who underwent RH treatment, comparing their outcomes to a control group of untreated patients with the dry form of AMD. The researchers aimed to assess the impact of RH on visual acuity, retinal function, and disease progression.

Promising Results: Improved Visual Acuity and Reduced Disease Progression

The study revealed encouraging findings, showing a significant improvement in best-corrected visual acuity (BCVA) in treated patients after 2.5 years. While no significant changes were observed in scotopic activity, cone response and paramacular activity exhibited significant improvements in the treated group. Importantly, no progression from dry to wet AMD was observed in the treated patients during the 2.5-year follow-up period. The researchers also observed a reduction in the area of drusenoid retinal pigment epithelium detachment, a hallmark of dry AMD progression.

A Glimpse into the Desert of Macular Degeneration: Hope for a Brighter Future

The study suggests that RH therapy may hold promise for improving visual acuity and potentially slowing down disease progression in patients with nonvascular AMD. The positive impact on BCVA and the reduction in drusenoid detachment provide encouraging signs. However, the researchers acknowledge the need for larger and more controlled studies to further evaluate the long-term efficacy and safety of RH treatment. This research offers a glimmer of hope for those affected by AMD, highlighting the potential of RH as a therapeutic avenue for this debilitating condition.

Dr.Camel's Conclusion

Rheohaemapheresis (RH) may hold promise for treating nonvascular age-related macular degeneration (AMD), as it has shown potential for improving visual acuity and reducing disease progression. However, further research is needed to confirm these findings and fully understand the long-term efficacy and safety of RH therapy.

Date :
  1. Date Completed 2013-09-18
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

23357162

DOI: Digital Object Identifier

10.1016/j.atherosclerosissup.2012.10.023

Related Literature

SNS
PICO Info
in preparation
Languages

English

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