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Salvage radical prostatectomy as management of locally recurrent prostate cancer: outcomes and complications.

Author: PrasadSandip M, RosoffJames S, SavageStephen J

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Salvage radical prostatectomy (SRP) is a potentially curative option for radiorecurrent localized prostate cancer. The ideal candidate for SRP has a life expectancy greater than 10 years, a PSA < 10 ng/ml and whose initial clinical staging was T1 or T2. The complication rate is high but decreasing, urinary continence rates range from 36 to 81%, erectile function is generally poor with less than 30% regaining adequate function. The 5-year biochemical recurrence-free probability ranged from 37 to 55% and the estimated cancer-specific survival at 10 years ranged from 70 to 83%.
Paper Details　
Original Abstract of the Article :
PURPOSE: Management of prostate cancer following radiation therapy remains challenging, especially for younger men or those with life expectancy greater than 10 years. We outline the efficacy, safety and adequacy of radical prostatectomy for the treatment of radiorecurrent localized prostate cancer....See full text at original site
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引用元：
https://doi.org/10.1007/s00345-013-1029-z

データ提供：米国国立医学図書館（NLM）

Salvage Radical Prostatectomy: A Second Chance for Men with Prostate Cancer

Prostate cancer, a common malignancy affecting men, can sometimes recur after radiation therapy. This systematic review explores the efficacy, safety, and appropriateness of salvage radical prostatectomy (SRP), a surgical procedure to remove the prostate gland, as a treatment option for locally recurrent prostate cancer following radiation therapy. The authors analyzed relevant published data from 1980 to 2012 to evaluate the outcomes and complications of SRP in this context.

SRP: A Curative Option for Selected Patients

The review found that SRP can be a potentially curative option for carefully selected patients with radiorecurrent localized prostate cancer. While SRP is associated with significant morbidity, including urinary incontinence and erectile dysfunction, it offers a chance for long-term disease-free survival. The authors emphasize the importance of careful patient selection and referral to experienced surgeons to maximize the benefits and minimize the risks of SRP.

Navigating the Risks and Benefits of SRP

This review highlights the complexities involved in managing prostate cancer after radiation therapy. SRP emerges as a potentially curative option, but it carries significant risks and requires careful consideration of individual patient factors. The authors emphasize the importance of individualized decision-making and a multidisciplinary approach to optimizing patient outcomes.

Dr. Camel's Conclusion

Prostate cancer, like a desert sandstorm, can be unpredictable and challenging. SRP, like a skilled navigator, can guide patients through this challenging terrain, offering a path to recovery. However, the journey is not without its risks and requires careful planning. This review provides valuable insights into the potential benefits and challenges of SRP, empowering both patients and healthcare professionals to make informed decisions about this treatment option.

Date :
  1. Date Completed 2014-09-30
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

23358790

DOI: Digital Object Identifier

10.1007/s00345-013-1029-z

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Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

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