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European guidelines for prevention and management of influenza in hematopoietic stem cell transplantation and leukemia patients: summary of ECIL-4 (2011), on behalf of ECIL, a joint venture of EBMT, EORTC, ICHS, and ELN.

Author: CordonnierC, EngelhardD, LjungmanP, MohtyB, de la CamaraR

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

These evidence-based guidelines from the 4th European Conference of Infections in Leukemia (ECIL-4) provide recommendations for the prevention and management of influenza infections in leukemia patients and hematopoietic stem cell transplantation recipients. Key recommendations include using real-time reverse-transcription polymerase chain reaction for diagnosis, early antiviral therapy with neuraminidase inhibitors, and annual vaccination for patients, household contacts, and hospital staff.
Paper Details　
Original Abstract of the Article :
Influenza may cause severe disease and mortality in leukemia patients and in hematopoietic stem cell transplantation recipients. The 4th European Conference of Infections in Leukemia (ECIL-4) has developed evidence-based guidelines for prevention and management of influenza infections in these patie...See full text at original site
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引用元：
https://doi.org/10.1111/tid.12054

データ提供：米国国立医学図書館（NLM）

Protecting Against Influenza: Navigating the Desert of Immune Compromise

Influenza can pose a significant threat to individuals with weakened immune systems, such as those undergoing hematopoietic stem cell transplantation or leukemia treatment. This study provides guidelines for the prevention and management of influenza infections in these high-risk patients. The authors, representing a collaboration of European organizations, developed evidence-based recommendations based on current medical knowledge. Their guidelines highlight the importance of early diagnosis, prompt treatment, and effective preventive measures.

Combatting the Desert Storm of Influenza

The guidelines emphasize the importance of real-time reverse-transcription polymerase chain reaction (RT-PCR) as the diagnostic test of choice for influenza. The authors also recommend neuraminidase inhibitors, such as oseltamivir and zanamivir, as the most effective therapeutic agents for influenza. They advocate for annual vaccination for patients, household contacts, and hospital staff to minimize the risk of infection.

Staying Safe in the Desert of Immune Vulnerability

The study's recommendations are crucial for protecting individuals with weakened immune systems from the dangers of influenza. By following these guidelines, healthcare professionals can provide effective care and minimize the risks associated with influenza infection.

Dr.Camel's Conclusion

Influenza can be a formidable foe, especially for those who are already battling a health challenge. These guidelines offer a vital roadmap for navigating the desert of immune compromise, providing essential strategies for prevention and management. By following these recommendations, healthcare professionals and patients can work together to minimize the risks of influenza infection and ensure the best possible outcomes.

Date :
  1. Date Completed 2014-01-21
  2. Date Revised 2013-06-03
Further Info :

Pubmed ID

23363310

DOI: Digital Object Identifier

10.1111/tid.12054

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Languages

English

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