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Rabies neutralizing antibody after 2 intradermal doses on days 0 and 21 for pre-exposure prophylaxis.
Author: KhawplodPakamatz, TantawichienTerapong, TepsumethanonSaowaluck, UdomchaisakulPiyada, WongsarojPatarapha
Original Abstract of the Article :
Pre-exposure prophylaxis is recommended for people who will be exposed to rabies virus in the laboratory or who will contact with mammals. World Health Organization recommends 2 doses of a cell-culture rabies vaccine given 1 week apart, and a third booster dose given 2-3 weeks later. Neutralizing an...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.vaccine.2013.01.035
データ提供:米国国立医学図書館(NLM)
Streamlining Rabies Prophylaxis: A Two-Visit Intradermal Regimen
The fight against rabies, a deadly disease transmitted through the bite of infected animals, requires a robust and effective prophylactic strategy. This research, like a diligent researcher seeking to optimize a life-saving treatment, investigates the immunogenicity and safety of a two-visit intradermal regimen for pre-exposure rabies prophylaxis. The authors, like skilled navigators charting a new course, compare the efficacy of this regimen to the conventional intramuscular regimen, seeking to streamline the vaccination process while maintaining robust protection.
A More Convenient Path to Rabies Protection: Two-Visit Intradermal Regimen
The findings, like a clear trail through a dense forest, reveal that the two-visit intradermal regimen is both safe and immunogenic, offering a more convenient and cost-effective option for pre-exposure rabies prophylaxis. The researchers, like meticulous scientists analyzing a complex experiment, carefully compare the antibody titers of individuals receiving the two-visit intradermal regimen to those receiving the conventional intramuscular regimen, finding no significant difference in immune response. This discovery, like a hidden oasis in a desert, offers a more convenient and accessible path to rabies protection, reducing the burden on both patients and healthcare systems.
A More Efficient Approach to Rabies Prevention
This research, like a bridge connecting two distant shores, provides a more efficient and accessible approach to rabies prevention. The findings, like a compass guiding travelers through uncharted territory, highlight the potential of the two-visit intradermal regimen to streamline the vaccination process while maintaining robust protection. This knowledge, like a valuable resource discovered in the desert, empowers us to make informed decisions about rabies prophylaxis, ensuring that individuals at risk are protected efficiently and effectively.
Dr. Camel's Conclusion
This study demonstrates the safety and effectiveness of a two-visit intradermal regimen for pre-exposure rabies prophylaxis, offering a more convenient and cost-effective alternative to the conventional intramuscular regimen. The research, like a well-paved path through a challenging landscape, provides a streamlined approach to rabies prevention, ensuring that individuals at risk are protected efficiently and effectively.
Date :
- Date Completed 2013-08-22
- Date Revised 2022-03-30
Further Info :
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English
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