Double-blind placebo-controlled study of olsalazine in the treatment of ulcerative colitis.

Author: DasK M, MolinasS, ZinbergJ

Paper Details 
Original Abstract of the Article :
Olsalazine is a compound consisting of two 5-amino salicylate (5-ASA) molecules linked by an azo bond, which, administered orally, is split by colonic bacteria to liberate 5-ASA. It lacks the sulfapyridine moiety found in sulfasalazine. Using a specific protocol, we conducted a randomized, double-bl...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/2337059

データ提供:米国国立医学図書館(NLM)

Olsalazine: A Potential Treatment for Ulcerative Colitis

This study explores the efficacy of olsalazine, a drug containing 5-aminosalicylate (5-ASA), in treating patients with ulcerative colitis, an inflammatory bowel disease. The researchers conducted a randomized, double-blind, placebo-controlled trial to compare the effects of olsalazine to placebo in patients with mild to moderate ulcerative colitis.

Olsalazine: A Promising Therapeutic Option

The study results suggest that olsalazine may be an effective treatment option for ulcerative colitis, showing significant improvement in clinical symptoms and endoscopic findings compared to placebo. This research provides valuable insights into the potential benefits of this drug for managing this chronic condition. Imagine a desert landscape ravaged by the fiery sands of ulcerative colitis. Olsalazine, like a refreshing oasis, can offer respite and relief from the symptoms of this debilitating disease.

Managing Ulcerative Colitis: A Collaborative Approach

Ulcerative colitis can be a challenging condition to manage, and this research highlights the importance of exploring new therapeutic options. Understanding the efficacy of different treatments, including olsalazine, is crucial for providing patients with personalized care and optimal management strategies.

Dr. Camel's Conclusion

This research is like a caravan crossing the desert, carrying the promise of relief for those struggling with ulcerative colitis. Olsalazine, a potential oasis in this challenging journey, offers hope for a brighter future for those affected by this chronic condition.

Date :
  1. Date Completed 1990-06-14
  2. Date Revised 2012-11-15
Further Info :

Pubmed ID

2337059

DOI: Digital Object Identifier

2337059

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.