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Paper Details

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Paper Details

Sex-difference and the effects of smoking and oral contraceptive steroids on the kinetics of diflunisal.

Author: HermanR J, MacdonaldJ I, VerbeeckR K

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Diflunisal clearance was significantly higher in men and women on oral contraceptives compared to control women. Smoking also increased diflunisal clearance, but reduced total urinary recovery.

Paper Details　

Original Abstract of the Article :

The single dose pharmacokinetics of diflunisal were studied in 4 groups of 6 young volunteers: control men, control women, women taking low estrogen oral contraceptive steroids (OCS), and women smokers (10-20 cigarettes day). The plasma clearance of diflunisal was significantly higher in men (0.169 ...See full text at original site

Dr.Camel's Paper Summary Blog

in preparation

Date :

Date Completed 1990-06-20
Date Revised 2019-08-13

Further Info :

Pubmed ID

DOI: Digital Object Identifier

10.1007/BF00265980

Related Literature

Article Analysis

・Effects of diflunisal

SNS

PICO Info

in preparation

Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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