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Cyproheptadine for prevention of neuropsychiatric adverse effects of efavirenz: a randomized clinical trial.
Author: AkhondzadehShahin, AlimadadiAbbas, DabaghzadehFatemeh, GhaeliPadideh, JafariSirous, KhaliliHossein, KhazaeipourZahra
Original Abstract of the Article :
Cyproheptadine prevention of the neuropsychiatric adverse effects of an antiretroviral regimen including efavirenz has been evaluated in a randomized clinical trial. Twenty-five patients (16 males and 9 females with mean±SD ages of 36±9 years) in a cyproheptadine group, and 26 patients (17 males and...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1089/apc.2012.0410
データ提供:米国国立医学図書館(NLM)
A Beacon of Hope for Efavirenz Side Effects: Cyproheptadine's Role
The treatment of HIV is a constant journey through a desert of challenges, with side effects often a major obstacle. This study, like a seasoned desert guide, explores the effectiveness of cyproheptadine in preventing neuropsychiatric adverse effects associated with efavirenz, a common antiretroviral drug. The authors, like meticulous cartographers, document the results of a randomized clinical trial, revealing cyproheptadine's potential to alleviate depression, anxiety, and sleep disturbances in HIV-positive patients.
Cyproheptadine: A Cooling Oasis in the Desert of Efavirenz Side Effects
This study, like a wellspring in a parched desert, highlights the potential benefits of cyproheptadine in mitigating the debilitating neuropsychiatric side effects of efavirenz. The authors, like skilled desert navigators, demonstrate that cyproheptadine significantly decreases scores on various scales, including Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, and Pittsburgh Sleep Quality Inventory, indicating its potential to improve patients' overall well-being.
Living Well with HIV: Finding Balance in the Desert
This study, like a compass guiding travelers through a vast and unforgiving desert, offers valuable insight into the management of HIV. The authors, like seasoned desert guides, emphasize the importance of minimizing the negative side effects of antiretroviral therapies, ensuring that patients can navigate their treatment journey with improved quality of life. This study, like a beacon of hope, reminds us that the pursuit of optimal health requires a holistic approach, taking into account not only the disease itself but also the impact of its treatment on patients' overall well-being.
Dr. Camel's Conclusion
This study, like a camel navigating a challenging desert, offers a valuable glimpse into the complexities of HIV treatment. Cyproheptadine, like a refreshing oasis, emerges as a potential solution for mitigating the neuropsychiatric side effects of efavirenz. However, the study, like a desert traveler, reminds us that further research is necessary to fully understand the long-term impact of this medication.
Date :
- Date Completed 2013-07-01
- Date Revised 2020-12-09
Further Info :
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