Randomised clinical trial: once- vs. twice-daily prolonged-release mesalazine for active ulcerative colitis.

Author: , AouchetaD, DewitO, FlouriéB, HagègeH, HébuterneX, KuyvenhovenJ P, MaetzD, MascleeA A M, PierikM J, ProbertC S, TanT G, TucatG

Paper Details 
Original Abstract of the Article :
BACKGROUND: Aminosalicylates are first-choice treatment for mild-to-moderately active ulcerative colitis (UC); however, multi-dosing regimens are inconvenient. AIM: To compare the efficacy and safety of once- (OD) vs. twice- (BD) daily prolonged-release mesalazine (Pentasa, Ferring, Saint-Prex, Swi...See full text at original site
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引用元:
https://doi.org/10.1111/apt.12266

データ提供:米国国立医学図書館(NLM)

Ulcerative Colitis: Finding a More Convenient Path to Remission

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, and aminosalicylates are a common treatment option. This study investigates the effectiveness of a once-daily prolonged-release mesalazine regimen compared to a twice-daily regimen. It's like finding a shortcut across the desert—looking for a more convenient and efficient route to reach the desired destination.

Once-Daily Mesalazine: A Streamlined Approach

The study found that the once-daily regimen was as effective as the twice-daily regimen in inducing remission in patients with mild-to-moderate UC. This is like finding a well-paved road through the desert—reducing the need for frequent stops and detours. The findings suggest that a once-daily regimen could improve patient convenience and adherence to treatment.

Convenience and Compliance: Key Ingredients for Success

This study underscores the importance of patient convenience and compliance in treatment success. Making treatment regimens more manageable can significantly improve patient outcomes. It's like finding a well-stocked oasis with easy access—making the journey more pleasant and ensuring success.

Dr. Camel's Conclusion

This study offers a promising alternative for patients with ulcerative colitis, demonstrating that a once-daily prolonged-release mesalazine regimen can effectively induce remission while improving patient convenience and compliance. This research highlights the importance of considering patient needs and preferences in designing treatment plans. It's like finding a well-worn path across the desert, leading to a more comfortable and successful journey for patients.

Date :
  1. Date Completed 2013-09-10
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

23451806

DOI: Digital Object Identifier

10.1111/apt.12266

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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