The role of chemotherapy including ifosfamide for ovarian carcinoma. Austrian Collab. Ovarian Cancer Study Group.

Author: DittrichC, KarrerK, SalzerH, SeveldaP

Paper Details 
Original Abstract of the Article :
On the basis of the results of earlier studies, 30 departments of gynecology have been cooperating nationwide in Austria since 1980 to promote the use of adjuvant chemotherapy after surgery for cure of ovarian carcinoma in early stages and the role of lymph node dissection and of second-look operati...See full text at original site
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引用元:
https://doi.org/10.1007/BF00685413

データ提供:米国国立医学図書館(NLM)

Chemotherapy for Ovarian Carcinoma: Adjuvant Treatment and Staging

Ovarian carcinoma is a serious and often challenging-to-treat cancer. This study investigates the role of chemotherapy, including ifosfamide, in the treatment of ovarian carcinoma. The researchers highlight the importance of adjuvant chemotherapy after surgery for cure in early stages, as well as the role of lymph node dissection and second-look operation. They analyze data from over 160 patients treated with adjuvant chemotherapy after radical surgery for stages I and II ovarian carcinoma, demonstrating that only highly differentiated tumors in stage Ia can be cured by surgery alone. This underlines the necessity of thorough staging for effective treatment. The study further investigates the therapeutic efficacy of different chemotherapy regimens, comparing sequential alternating drug regimens with Adriamycin-cisplatin + vincristine-cyclophosphamide + high-dose methotrexate, Adriamycin-cyclophosphamide, and Adriamycin-cisplatin. The study also explores the use of high-dose ifosfamide in pilot studies.

The Importance of Adjuvant Chemotherapy for Ovarian Carcinoma

This study underscores the importance of adjuvant chemotherapy after surgery for ovarian carcinoma. The findings demonstrate that surgery alone is not sufficient to cure most cases of ovarian carcinoma, especially in stages I and II. Adjuvant chemotherapy plays a crucial role in eradicating residual cancer cells and improving long-term survival. This study also emphasizes the importance of accurate staging to guide treatment decisions and ensure optimal outcomes for patients.

Navigating Ovarian Carcinoma: Understanding Treatment Options and Seeking Support

Ovarian carcinoma can be a challenging diagnosis, but understanding treatment options and seeking support can make a significant difference. This study highlights the importance of adjuvant chemotherapy, accurate staging, and multidisciplinary approaches to treatment. It is crucial for individuals diagnosed with ovarian carcinoma to work closely with healthcare professionals to develop an individualized treatment plan and receive comprehensive support throughout their journey.

Dr. Camel's Conclusion

This study provides valuable insights into the treatment of ovarian carcinoma, a complex and often challenging cancer. Just as a camel navigates the vast desert landscape, researchers are continuously seeking new and effective approaches to treating this disease. This study emphasizes the importance of multidisciplinary care, accurate staging, and adjuvant chemotherapy in improving outcomes for patients with ovarian carcinoma. By understanding the complexities of this disease and working collaboratively with healthcare professionals, individuals diagnosed with ovarian carcinoma can navigate their journey with strength and hope.

Date :
  1. Date Completed 1990-07-11
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

2347046

DOI: Digital Object Identifier

10.1007/BF00685413

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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