Post-acute effectiveness of lithium in pediatric bipolar I disorder.

Author: ClemonsTraci E, FindlingRobert L, FrazierJean A, KafantarisVivian, KowatchRobert, McNamaraNora K, PavuluriMani, RowlesBrieana M, SikichLinmarie, Taylor-ZapataPerdita

Paper Details 
Original Abstract of the Article :
OBJECTIVE: This study examined the long-term effectiveness of lithium for the treatment of pediatric bipolar disorder within the context of combination mood stabilizer therapy for refractory mania and pharmacological treatment of comorbid psychiatric conditions. METHODS: Outpatients, ages 7-17 year...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609605/

データ提供:米国国立医学図書館(NLM)

Lithium: A Long-Term Treatment for Pediatric Bipolar Disorder?

This study delves into the realm of pediatric bipolar disorder, a condition that can be quite a challenge to navigate. The researchers were interested in exploring the effectiveness of lithium as a long-term treatment for these young patients, especially when combined with other mood stabilizers to tackle those stubborn cases of mania. They used a combination of open-label treatment phases and a standardized algorithm for prescribing additional medications as needed. The results are quite intriguing! The study found that patients who initially responded well to lithium continued to benefit from it over a longer period, but those who only partially responded to it didn't see much improvement even with the addition of other medications. This suggests that lithium could be a viable long-term treatment option for a subset of pediatric bipolar disorder patients, but more research is needed to understand why it works better for some than for others.

Lithium: A Beacon of Hope for Some, But Not All

The study found that lithium treatment was associated with a significant reduction in manic symptoms in patients who responded well to it in the initial phase. This is a significant finding, considering the impact of bipolar disorder on young lives. Almost two-thirds of the patients who responded well to lithium in the short-term continued to experience symptom improvement during the continuation phase, highlighting the potential for long-term effectiveness.

Navigating the Desert of Bipolar Disorder

Navigating the complexities of pediatric bipolar disorder can be like traversing a vast, unpredictable desert. While lithium may provide a welcome oasis for some patients, others may find it's not the right solution for their journey. The researchers emphasize the importance of carefully monitoring patients and adjusting their treatment plan as needed. The most common side effects were vomiting, headache, abdominal pain, and tremor. These symptoms are like the occasional sandstorm in the desert, which can be managed with the right preparation and support.

Dr.Camel's Conclusion

This study provides valuable insight into the potential benefits and limitations of lithium as a long-term treatment for pediatric bipolar disorder. It serves as a reminder that the path to recovery is often complex and requires a personalized approach. While lithium may be a helpful tool for some patients, further research is needed to understand its full potential and to identify better ways to predict who will benefit most from this treatment.

Date :
  1. Date Completed 2013-09-13
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23510444

DOI: Digital Object Identifier

PMC3609605

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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