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Practical issues for the use of tranexamic acid in total knee arthroplasty: a systematic review.

Author: ChangChong Bum, KimTae Kyun, KohIn Jun

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review examined the use of tranexamic acid (TNA) in total knee arthroplasty (TKA). The review found that TNA can reduce blood loss, but there is no difference in effectiveness between systemic and topical administration. The effectiveness of TNA may vary depending on the dose and timing of administration. The review also found that TNA is safe at all reported doses, timings, and routes of administration with respect to deep vein thrombosis and pulmonary embolism.
Paper Details　
Original Abstract of the Article :
This systematic review was undertaken to answer three specific questions relating to the clinical values of tranexamic acid (TNA) in total knee arthroplasty (TKA): (1) Whether there are differences in blood-saving effects between the systemic and topical administrations; (2) Whether blood-saving eff...See full text at original site
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引用元：
https://doi.org/10.1007/s00167-013-2487-y

データ提供：米国国立医学図書館（NLM）

Tranexamic Acid: A Blood-Saving Agent in Total Knee Arthroplasty

This research explores the use of tranexamic acid (TNA) in total knee arthroplasty (TKA), a common surgical procedure. It's like searching for a way to minimize blood loss in the midst of a desert surgery. The study systematically reviews the available evidence to address key questions about the effectiveness and safety of TNA in TKA. The review explores the optimal routes, doses, and timing of administration to maximize the blood-saving benefits of TNA.

Tranexamic Acid: A Valuable Tool for Minimizing Blood Loss

This research highlights the potential of TNA as a blood-saving agent in TKA, potentially reducing the need for blood transfusions. It's like finding a way to conserve precious resources in a desert environment. The study emphasizes the importance of considering the potential benefits and risks of TNA, as well as the need for individualized treatment plans based on patient characteristics.

Navigating Joint Replacement Surgery: A Guide to Safety and Recovery

The findings of this research provide valuable insights for managing blood loss and optimizing recovery following TKA. It's like navigating a desert path to recovery, knowing the potential risks and finding ways to minimize them. The study encourages careful consideration of the use of TNA in TKA, weighing the potential benefits against the potential risks and ensuring a safe and effective surgical experience for patients.

Dr.Camel's Conclusion

This research examines the role of tranexamic acid in total knee arthroplasty, a common surgical procedure. It's like exploring the desert of surgical science, seeking ways to improve patient outcomes. The study highlights the potential benefits of TNA in minimizing blood loss and optimizing recovery, emphasizing the importance of individualized treatment plans and a careful assessment of the potential risks and benefits.

Date :
  1. Date Completed 2014-12-08
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

23542923

DOI: Digital Object Identifier

10.1007/s00167-013-2487-y

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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