Paper Details 
Original Abstract of the Article :
Cardiac surgery exerts a significant strain on the blood bank services and is a model example in which a multi-modal blood-conservation strategy is recommended. Significant bleeding during cardiac surgery, enough to cause re-exploration and/or blood transfusion, increases morbidity and mortality. Hy...See full text at original site
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引用元:
https://doi.org/10.4103/0971-9784.109749

データ提供:米国国立医学図書館(NLM)

Antifibrinolytics in Cardiac Surgery: Balancing the Scales

Cardiac surgery, a delicate dance of life and death, poses significant challenges for blood bank services. The delicate balance of blood clotting and bleeding, often disrupted during surgery, can lead to complications like re-exploration and blood transfusions, increasing the risk of mortality. This study dives deep into the world of antifibrinolytic agents, those heroic molecules that help control bleeding during cardiac surgery. The research delves into the pros and cons of various antifibrinolytic agents, including aprotinin, tranexamic acid (TA), and epsilon amino caproic acid (EACA), highlighting their effectiveness in reducing blood loss and their potential side effects. The authors emphasize the need to carefully consider the risk-benefit profile of each agent, tailoring treatment to the individual patient's needs and the specific circumstances of the surgery.

A delicate dance of life and death

This research reveals that antifibrinolytic agents, while effective in reducing blood loss during cardiac surgery, come with a set of potential side effects. Each agent has its own strengths and weaknesses, with aprotinin being the most potent but potentially risky, TA being a middle ground, and EACA being the least effective but also the safest. The study underscores the importance of personalized medicine, emphasizing the need to select the most suitable agent for each patient based on their individual needs and the nature of the surgery.

Balancing the scales: Finding the right agent for the right patient

This study sheds light on the complex interplay between blood clotting and bleeding during cardiac surgery. Understanding the individual characteristics of various antifibrinolytic agents and their potential side effects is crucial for making informed decisions about patient care. These findings highlight the importance of individualized treatment plans, taking into account the unique needs of each patient.

Dr.Camel's Conclusion

Cardiac surgery is a delicate dance where blood clotting and bleeding need to be carefully balanced. This research explores the fascinating world of antifibrinolytic agents, showcasing their efficacy and potential risks. It’s like choosing the right camel for a long journey through the desert; some are faster but less reliable, while others are slower but more dependable. Finding the perfect balance is key for a successful and safe journey.

Date :
  1. Date Completed 2013-09-26
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

23545866

DOI: Digital Object Identifier

10.4103/0971-9784.109749

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SNS
PICO Info
in preparation
Languages

English

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