Dissociative disorder induced by clarithromycin combined with rabeprazole in a patient with gastritis.

A Desert of Dissociation: Clarithromycin and Rabeprazole's Unforeseen Effects

Clarithromycin and rabeprazole, commonly used medications for treating gastrointestinal conditions, are generally considered safe. However, this case report highlights a potentially serious side effect of combining these medications. A patient experiencing gastritis who received clarithromycin and rabeprazole for Helicobacter pylori infection developed acute psychotic symptoms of dissociative disorder, including disorientation, fragmented thinking, and amnesia.

A Shifting Landscape of Medication Interactions

This case report raises concerns about the potential for neurotoxicity when combining clarithromycin and rabeprazole, particularly in susceptible individuals. It underscores the importance of careful consideration of medication interactions, particularly when treating patients with underlying conditions.

Navigating the Desert of Medication Safety

Imagine a desert traveler carrying a map that doesn't account for hidden dangers, like a treacherous sandstorm or a hidden oasis. This case report highlights the importance of navigating the desert of medication interactions with caution and awareness. It reminds us that seemingly safe medications can have unexpected consequences when combined, emphasizing the need for close monitoring and informed decision-making in clinical practice.

Dr.Camel's Conclusion

This case report serves as a stark reminder of the importance of understanding potential medication interactions. While clarithromycin and rabeprazole are generally considered safe, this case highlights the potential for neurotoxicity when these medications are combined, emphasizing the need for vigilance and careful consideration of medication interactions in clinical practice.