Pharmacokinetic and pharmacodynamic effects of prasugrel in healthy Korean males.

Author: ChoiHyunah C, GuNamyi, KawakatsuEiji, KellyRonan P, ParkKyung Woo, PayneChristopher, PintonPhilippe, SmallDavid S, YuKyung-Sang

Paper Details 
Original Abstract of the Article :
Prasugrel is a thienopyridine for treatment of acute coronary syndromes in patients undergoing percutaneous coronary intervention. Higher concentrations of prasugrel's active metabolite (R-138727) have been observed in Asian than white subjects. The primary objective was to investigate pharmacokinet...See full text at original site
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引用元:
https://doi.org/10.1097/FJC.0b013e318290d9e1

データ提供:米国国立医学図書館(NLM)

Prasugrel: A Journey into the World of Thienopyridines

The field of cardiology is a constant pursuit of innovative therapies to combat heart disease. This study delves into the fascinating world of prasugrel, a thienopyridine medication used to treat acute coronary syndromes in patients undergoing percutaneous coronary intervention. Like a camel navigating a challenging desert landscape, researchers seek to understand the intricate workings of this drug and its potential to improve patient outcomes. This study aimed to investigate the pharmacokinetics of prasugrel's active metabolite (R-138727) in healthy Korean males. The authors sought to unveil the unique characteristics of this drug in a specific population, providing valuable insights for clinical practice.

Tailoring Treatment to the Individual

The study's findings suggest that the dosing strategies approved for white patients with acute coronary syndromes may be applicable to Asian patients. However, further research is needed to solidify this conclusion. This highlights the importance of considering individual factors when prescribing medications, recognizing the potential differences in drug metabolism and efficacy across various populations.

Understanding Medication Interactions

This study provides a glimpse into the intricate world of drug interactions. It serves as a reminder that we must consider the unique characteristics of individuals and their responses to medication. Consult with your healthcare professional to ensure that your medication regimen is safe and effective for you.

Dr.Camel's Conclusion

This research underscores the importance of individualized medicine, recognizing that what works for one person may not work for another. It's a journey that involves careful observation, meticulous analysis, and a commitment to tailoring treatment plans to the unique needs of each patient.

Date :
  1. Date Completed 2013-12-11
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

23594968

DOI: Digital Object Identifier

10.1097/FJC.0b013e318290d9e1

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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