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A 250 μg/week dose of vitamin D was as effective as a 50 μg/d dose in healthy adults, but a regimen of four weekly followed by monthly doses of 1250 μg raised the risk of hypercalciuria.

Author: InnisSheila M, KimlinMichael, LockeJames P, ParsonsHoward, SmithScott M, ZwartSara R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

This study compared different ways of taking vitamin D supplements (daily, weekly, or weekly/monthly) in healthy adults. Taking vitamin D weekly (up to 10,000 IU) was as effective as daily doses in raising vitamin D levels and didn't increase the risk of high calcium in the urine. However, weekly doses of 50,000 IU were associated with higher calcium levels in the urine, especially in people with a BMI over 26.
Paper Details　
Original Abstract of the Article :
The risk of vitamin D insufficiency is increased in persons having limited sunlight exposure and dietary vitamin D. Supplementation compliance might be improved with larger doses taken less often, but this may increase the potential for side effects. The objective of the present study was to determi...See full text at original site
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引用元：
https://doi.org/10.1017/S000711451300113X

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2013-12-23
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

23595003

DOI: Digital Object Identifier

10.1017/S000711451300113X

SNS
PICO Info
in preparation
Languages

English

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