Use of alpha-tocopherol esters for topical vitamin E treatment: evaluation of their skin permeation and metabolism.

Author: Beit-YannaiElie, Ben-ShabatShimon, KazdanYolia, SintovAmnon C

Paper Details 
Original Abstract of the Article :
OBJECTIVES: The aim of this work was to investigate new pro-vitamins based on α-tocopherol (α-Toc) and fatty acids, and to compare their properties with those of α-tocopherol acetate (α-TAc). METHODS: Skin levels of α-Toc-fatty acid ester conjugates, total α-Toc and endogenous α-Toc were measured i...See full text at original site
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引用元:
https://doi.org/10.1111/jphp.12027

データ提供:米国国立医学図書館(NLM)

Topical Vitamin E Treatment: A New Frontier in Skin Care

The field of dermatology is always seeking innovative ways to enhance skin health. This study explores the potential of α-tocopherol esters, or vitamin E derivatives, as topical treatments. The researchers investigated the skin permeation and metabolism of these esters, aiming to find a stable and effective alternative to α-tocopherol acetate (α-TAc). Their findings suggest that certain α-tocopherol-fatty acid conjugates effectively penetrate the skin while offering improved safety compared to α-TAc.

The Power of Unsaturated Fatty Acids

The research indicates that α-tocopherol conjugates with unsaturated fatty acids, such as α-Toc oleate, may be a superior option for topical vitamin E delivery. These esters exhibit comparable skin permeation to α-TAc, but with a significant safety advantage. The results are promising, suggesting that these conjugates could offer a more effective and safer way to deliver vitamin E benefits to the skin.

A Smooth and Radiant Desert Glow

Imagine a desert landscape where the air is dry and the sun is harsh. Just as applying lotion helps protect our skin from the elements, topical vitamin E can offer valuable benefits for our skin. This study demonstrates the potential of α-tocopherol esters to deliver vitamin E effectively and safely, promoting healthy and radiant skin.

Dr.Camel's Conclusion

This research delves into the promising realm of topical vitamin E treatment, exploring the potential of α-tocopherol esters as a safer and more effective alternative to α-tocopherol acetate. The findings highlight the benefits of α-tocopherol conjugates with unsaturated fatty acids, suggesting a new frontier in skin care.

Date :
  1. Date Completed 2013-10-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

23600381

DOI: Digital Object Identifier

10.1111/jphp.12027

Related Literature

SNS
PICO Info
in preparation
Languages

English

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