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Use of alpha-tocopherol esters for topical vitamin E treatment: evaluation of their skin permeation and metabolism.
Author: Beit-YannaiElie, Ben-ShabatShimon, KazdanYolia, SintovAmnon C
Original Abstract of the Article :
OBJECTIVES: The aim of this work was to investigate new pro-vitamins based on α-tocopherol (α-Toc) and fatty acids, and to compare their properties with those of α-tocopherol acetate (α-TAc). METHODS: Skin levels of α-Toc-fatty acid ester conjugates, total α-Toc and endogenous α-Toc were measured i...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/jphp.12027
データ提供:米国国立医学図書館(NLM)
Topical Vitamin E Treatment: A New Frontier in Skin Care
The field of dermatology is always seeking innovative ways to enhance skin health. This study explores the potential of α-tocopherol esters, or vitamin E derivatives, as topical treatments. The researchers investigated the skin permeation and metabolism of these esters, aiming to find a stable and effective alternative to α-tocopherol acetate (α-TAc). Their findings suggest that certain α-tocopherol-fatty acid conjugates effectively penetrate the skin while offering improved safety compared to α-TAc.
The Power of Unsaturated Fatty Acids
The research indicates that α-tocopherol conjugates with unsaturated fatty acids, such as α-Toc oleate, may be a superior option for topical vitamin E delivery. These esters exhibit comparable skin permeation to α-TAc, but with a significant safety advantage. The results are promising, suggesting that these conjugates could offer a more effective and safer way to deliver vitamin E benefits to the skin.
A Smooth and Radiant Desert Glow
Imagine a desert landscape where the air is dry and the sun is harsh. Just as applying lotion helps protect our skin from the elements, topical vitamin E can offer valuable benefits for our skin. This study demonstrates the potential of α-tocopherol esters to deliver vitamin E effectively and safely, promoting healthy and radiant skin.
Dr.Camel's Conclusion
This research delves into the promising realm of topical vitamin E treatment, exploring the potential of α-tocopherol esters as a safer and more effective alternative to α-tocopherol acetate. The findings highlight the benefits of α-tocopherol conjugates with unsaturated fatty acids, suggesting a new frontier in skin care.
Date :
- Date Completed 2013-10-28
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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