Paper Details

  1. Home
  2. Paper Details

Severe water intoxication secondary to the concomitant intake of non-steroidal anti-inflammatory drugs and desmopressin: a case report and review of the literature.

Author: FerranteEmanuele, IapichinoGaetano, MalchiodiElena, MantovaniGiovanna, NotoAndrea, PeccozPaolo Beck, SalaElisa, SpadaAnna, VerruaElisa

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report highlights the potential for severe hyponatremia and seizures in patients on desmopressin therapy for central diabetes insipidus when non-steroidal anti-inflammatory drugs (NSAIDs) are co-administered.
Paper Details　
Original Abstract of the Article :
Most of the clinical data on the safety profile of desmopressin (DDAVP), which is an effective treatment for both polyuric conditions and bleeding disorders, originate from studies on the tailoring of drug treatment, whereas few reports exist describing severe side effects secondary to drug-drug int...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/BF03401295

データ提供：米国国立医学図書館（NLM）

Water Intoxication: A Dangerous Desert Mirage

The desert is a place of extremes, where life can be sustained or jeopardized by the delicate balance of water. This research explores a case of severe water intoxication, a potentially life-threatening condition that can occur when the body's water balance is disrupted. The authors examine the case of a patient with central diabetes insipidus, a condition characterized by excessive urination, who developed severe hyponatremia, a condition where the sodium levels in the blood are too low, after taking non-steroidal anti-inflammatory drugs (NSAIDs) alongside desmopressin, a medication used to treat diabetes insipidus. Their research highlights the importance of careful medication management and understanding potential drug interactions.

Navigating the Desert of Drug Interactions

The study highlights the potential for a dangerous interaction between NSAIDs and desmopressin, a combination that can lead to severe water intoxication and potentially life-threatening consequences. This emphasizes the importance of consulting with a healthcare professional to discuss potential drug interactions and manage medication regimens effectively.

Staying Hydrated in the Desert

Water intoxication, like a deceptive desert mirage, can be dangerous. If you are taking desmopressin or any other medications, it's crucial to consult with your healthcare provider about potential interactions, side effects, and how to manage your hydration levels effectively.

Dr.Camel's Conclusion

This case study serves as a reminder of the potential dangers of drug interactions, particularly in the delicate desert of water balance. It highlights the importance of careful medication management and open communication with healthcare professionals to navigate the complexities of medication regimens and prevent potentially life-threatening situations.

Date :
  1. Date Completed 2013-11-19
  2. Date Revised 2019-05-07
Further Info :

Pubmed ID

23624139

DOI: Digital Object Identifier

10.1007/BF03401295

Related Literature

Article Analysis
・Side Effects of desmopressin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.