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Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children.

Author: CatesChristopher J, KarnerCharlotta

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Single inhaler therapy (SiT) with budesonide and formoterol was shown to reduce the risk of asthma exacerbations needing oral corticosteroids compared to fixed dose maintenance inhaled corticosteroids (ICS) and separate relief medication. However, the evidence for SiT reducing hospitalization is weak. There were more discontinuations due to adverse events on SiT compared to current best practice, but no significant differences in serious adverse events.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Traditionally inhaled treatment for asthma has used separate preventer and reliever therapies. The combination of formoterol and budesonide in one inhaler has made possible a single inhaler for both prevention and relief of symptoms (single inhaler therapy or SiT). OBJECTIVES: To assess...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357488/

データ提供：米国国立医学図書館（NLM）

Single Inhaler Therapy for Asthma: A New Oasis in the Desert of Respiratory Management

Asthma is a chronic respiratory condition that can significantly impact a person's quality of life. Traditional treatment has often involved separate inhalers for prevention and relief of symptoms. This study explores the efficacy and safety of a single inhaler therapy (SiT), combining formoterol and budesonide, for the management of asthma. The authors conducted a comprehensive review of clinical trials, comparing SiT to conventional treatment strategies, seeking to determine whether SiT offers a more efficient and effective approach to asthma management.

The Benefits of SiT: A Path to Improved Outcomes

The study's results suggest that SiT can be an effective and safe approach to asthma management, leading to a reduction in exacerbations requiring oral corticosteroids and a decrease in the need for inhaled corticosteroids. These findings highlight the potential of SiT to improve asthma control and reduce healthcare utilization. However, the study also notes that SiT may be associated with an increased risk of discontinuation due to adverse events.

Navigating the Desert of Asthma Treatment

This study provides valuable insights into the potential of SiT to improve asthma management, offering a new oasis in the desert of respiratory care. The findings encourage further research into the optimal use of SiT, with the goal of developing personalized treatment strategies that maximize effectiveness and minimize potential side effects.

Dr.Camel's Conclusion

The desert of asthma management is vast and often challenging. This study offers a glimmer of hope, highlighting the potential of SiT to improve asthma control and reduce healthcare utilization. While further research is needed to optimize the use of SiT, the findings suggest that this new approach may offer a more efficient and effective path to managing this chronic respiratory condition.

Date :
  1. Date Completed 2013-11-05
  2. Date Revised 2023-07-22
Further Info :

Pubmed ID

23633340

DOI: Digital Object Identifier

PMC10357488

Related Literature

Article Analysis
・Effective treatment of asthma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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