The pathophysiological and pharmacological basis of current drug treatment of migraine headache.

Author: ReddyDoodipala Samba

Paper Details 
Original Abstract of the Article :
Migraine is a common neurological syndrome that affects approximately 10-20% of the population. The pathophysiology of migraine is unclear. 5-hydroxytriptamine is a key mediator in the pathogenesis of migraine and thus 5-HT1-receptor agonists are the principal drugs for acute migraine therapy. There...See full text at original site
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引用元:
https://doi.org/10.1586/ecp.13.14

データ提供:米国国立医学図書館(NLM)

Navigating the Complex World of Migraine Treatment

This review explores the [pathophysiology and pharmacology of migraine headache], providing a comprehensive overview of current drug treatments. The authors discuss the role of [5-hydroxytriptamine (5-HT)] in migraine pathogenesis, highlighting the importance of [5-HT1-receptor agonists] in acute migraine therapy. The review further explores the various classes of drugs used for both acute and prophylactic treatment of migraine, emphasizing the need for new drugs with improved efficacy and reduced side effects.

A Symphony of Treatments: Navigating the Options for Migraine

This review provides a detailed overview of [current drug treatments for migraine]. The authors highlight the various classes of medications available, including over-the-counter analgesics, nonsteroidal anti-inflammatory drugs, triptans, ergot alkaloids, and prophylactic agents.

A Path Forward: The Quest for More Effective Migraine Treatments

This review underscores the ongoing need for [new and improved migraine treatments]. The authors highlight the need for drugs with enhanced efficacy, reduced side effects, and targeted mechanisms of action to address the diverse needs of migraine sufferers.

Dr.Camel's Conclusion

Migraine, like a desert storm, can disrupt life with its unpredictable and debilitating effects. This review, like a guidebook for navigating a treacherous desert, offers valuable insights into the current landscape of migraine treatment. The ongoing quest for more effective therapies continues, seeking to alleviate the suffering of millions who experience this common neurological condition.

Date :
  1. Date Completed 2013-11-07
  2. Date Revised 2013-05-09
Further Info :

Pubmed ID

23656340

DOI: Digital Object Identifier

10.1586/ecp.13.14

Related Literature

SNS
PICO Info
in preparation
Languages

English

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