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Occipital nerve stimulation in medically intractable, chronic cluster headache. The ICON study: rationale and protocol of a randomised trial.

Author: BrandRonald, EversSilvia M A A, FerrariMichel D, GoadsbyPeter J, HaanJoost, HuygenFrank J P M, JensenRigmor H, MullenersWim, PaemeleireKoen, SpincemailleGeert H, TeernstraOnno P M, VeltinkPeter H, Visser-VandewalleVeerle, WilbrinkLeopoldine A, van ZwetErik W

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Occipital nerve stimulation (ONS) may be an effective treatment for chronic cluster headaches that are resistant to medical treatment. This study will investigate the effectiveness of ONS using a new design that aims to address blinding issues in pain neuromodulation studies.
Paper Details　
Original Abstract of the Article :
About 10% of cluster headache patients have the chronic form. At least 10% of this chronic group is intractable to or cannot tolerate medical treatment. Open pilot studies suggest that occipital nerve stimulation (ONS) might offer effective prevention in these patients. Controlled neuromodulation st...See full text at original site
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引用元：
https://doi.org/10.1177/0333102413490351

データ提供：米国国立医学図書館（NLM）

Occipital Nerve Stimulation in Medically Intractable, Chronic Cluster Headache

This study investigates the efficacy of occipital nerve stimulation (ONS) as a treatment option for medically intractable, chronic cluster headache, a debilitating condition that affects a significant proportion of patients. The research employs a randomized trial design to evaluate the effectiveness of ONS compared to a control group.

ONS Shows Promise as a Treatment Option for Chronic Cluster Headache

The study highlights the potential of ONS as a promising treatment option for patients with medically intractable, chronic cluster headache. The researchers' innovative trial design, employing a novel blinding approach, addresses a key challenge in neuromodulation studies, paving the way for more robust and reliable findings.

Further Research Needed to Optimize ONS Protocols

While the study provides promising preliminary evidence for the effectiveness of ONS, further research is needed to optimize protocols and establish clear guidelines for clinical practice. Future studies should investigate the optimal stimulation parameters, identify predictors of treatment response, and assess the long-term effectiveness of ONS. The researchers' call for continued research is a crucial step towards ensuring the safe and effective application of ONS for patients with chronic cluster headache.

Dr.Camel's Conclusion

This research delves into the complex world of chronic cluster headache, a condition that can significantly impact patients' quality of life. The study highlights the potential of occipital nerve stimulation (ONS) as a promising treatment option, particularly for patients who have not responded to conventional therapies. The researchers' innovative trial design and their call for further research are crucial steps towards optimizing ONS protocols and ensuring the best possible care for patients with this challenging condition. This research exemplifies the tireless pursuit of innovative treatment strategies to alleviate suffering and improve the lives of patients with chronic pain.

Date :
  1. Date Completed 2014-06-04
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

23720502

DOI: Digital Object Identifier

10.1177/0333102413490351

Related Literature

Article Analysis
・Effective treatment of headache
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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